
Episode #32
The Science of Supplements and Longevity w/ Leonard Guarente, PhD
What separates evidence-based supplements from clever marketing—and what does the science really tell us about longevity? In this episode, I sit down with Dr. Leonard “Lenny” Guarente, MIT professor and co-founder and chief scientist of Elysium Health. Dr. Guarente is a pioneer in aging research whose work helped establish the connection between sirtuins, metabolism, and longevity. We explore: • How to evaluate the quality of a supplement • Why some supplements may not contain what their labels claim • How to determine whether a company is conducting credible research • What peer-reviewed studies can—and cannot—tell us • Why the reputation of the publishing journal matters • The relationship between sirtuins, NAD+, and aging • How to separate promising longevity science from industry hype Whether you’re curious about supplements, healthy aging, or the emerging science of longevity, this conversation offers a practical framework for evaluating claims and following the evidence. Learn more about Dr. Guarente’s research: https://biology.mit.edu/profile/leonard-p-guarente/ Explore Elysium Health’s published research and clinical trials: https://www.elysiumhealth.com/pages/science The information provided in Adding Years: Your Roadmap to Longevity is for informational and educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. The hosts and producers are not licensed medical professionals, dietitians, or healthcare providers. While some guests may be licensed medical professionals, they appear solely in an educational capacity and are not providing individualized medical care or establishing any healthcare provider–patient relationship.

