Bloody Minded

Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the fellows of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs. Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au

Bloody Minded is a health podcast hosted by Bloody Minded Crew, with 107 episodes on record and a Required Pod Score of 80.

Bloody Minded Crew hosts Bloody Minded, a health show with 107 episodes published.

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  Episode #106

  Episode 106 - Seal Team L | Chronic Lymphocytic Leukaemia (CLL)

  Sep 29, 202648 minS1

  Why do haematologists get excited over smudges on a film? What is the deal with that whole IGHV situation? Why is Bashar no longer welcome at the zoo? Join us as we find the answers to these common haematology questions and more in a foray into Chronic Lymphocytic Leukaemia! TIMESTAMPS 0:55 - No animals were harmed in the making of this bit 4:13 - Epidemiology of CLL 5:56 - Pathophysiology of CLL 11:42 - MBL 12:36 - SLL 15:54 - Clinical features of CLL 18:18 - Lab features of CLL 20:50 - Flow cytometry for CLL 23:46 - Staging of CLL 25:38 - Prognostication of CLL 27:38 - Indications for treatment in CLL 31:04 - Treatment approaches for CLL 41:53 - Response assessment in CLL 42:49 - Richter's transformation 44:47 - Take Home Messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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  Episode #105

  Episode 105 - Lymphoverview – An Overview of the Lymphoid Disorders

  Sep 22, 202643 minS1

  Welcome to the Land of the Lymphoid. Eighty-odd subtypes, one grid. Help us break our cellular pathways and journey further into our lymphoid season as we ask the only two questions that matter - B or T, fast or slow, forget the platypuses - and build the framework we'll be filling in for the rest of the series. Bring a hat, the savannah is hot. 0:52 - Lymphoid Planet 2:50 - Leukaemia vs Lymphoma 4:51 - Two Questions & A Recap 8:49 - Identifying a Cell 16:22 - Indolent vs Aggressive (and Super-Aggressive) 22:37 - Indolent B-Cell 23:21 - Aggressive B-Cell 25:27 - Indolent T-Cell 25:44 - Aggressive T-Cell 27:42 - Wait... what about Hodgkins 31:28 - A Framework 32:21 - General Lymphoma Workup 38:19 - Staging 40:12 - Review Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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  Episode #104

  Episode 104 - Immunology 102 | Lymphocyte Maturation & The Lymph Node

  Sep 15, 202630 minS1

  For the first time, Cale, Nick and Bashar have managed to maintain a contiguous thought across two different episodes and are returning to school - for the basics of immunology. But they’re not going back as teachers, no, the boys are going undercover as a naïve B-cell and following the journey to the lymph node. Will they be shunned to the uncool table like they were in high school? Can they avoid the murderous hunger games of the dark zone. Will they switch classes or somatically hypermutate? Find out on the next episode of 21 Ju… Lymph Node Street. TIMESTAMPS 0:53 - Disguise 101 5:10 - Naive B cells journey 7:56 - Lymph node anatomy refresher 13:31 - Activation of naive B cells 18:50 - Class switching 21:38 - Into the dark zone 24:45 - Diseases at the various stages of maturation 27:18 - Take Home Messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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  Episode #103

  Episode 103 - On The Wards: Breaking Bad . . . Cells | Tumour Lysis Syndrome

  Sep 1, 202643 minS1

  Have you been asked to review “TLS” bloods?? Are you concerned the nursing staff are pranking you with haematology bloods that don’t include a FBC or coags? Why could you possibly want to look at something that isn’t a cell count? What crazy person decided after hours bloods needed to be collected on ICE? And WHY ?!?! Join us for an On The Wards approach to dealing with those TDS TLS SOS calls. TIMESTAMPS: 0:56 - The team breaking stuff 3:40 - Episode overview 5:07 - Setting the scene 6:33 - The history of TLS 7:28 - (nailed it) 8:00 - Pathophysiology of TLS 10:41 - Mechanisms of renal injury in TLS 11:39 - Clinical consequences of TLS 12:46 - Diagnostic criteria in TLS 15:10 - Clinical TLS vs lab TLS 15:35 - Grading TLS 16:55 - Other clues of TLS 18:09 - Who is at risk of TLS? 23:15 - Prevention of TLS 24:27 - Allopurinol 26:58 - Rasburicase 33:03 - Fluids fluids fluids 33:44 - Deciding who gets prophylaxis 35:50 - What ARE TLS bloods? 36:31 - What to do with a TLS on the ward 40:05 - Take home messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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  Episode #102

  Episode 102 - Reign in Blood | Heavy Metals in Haematology

  Aug 18, 202632 minS1

  It’s the heaviest matter of haematology as we look at the role of heavy metals in our favourite metalloenzymes. What - you don’t have a favourite metalloenzyme? But nothing else matters?! Anyway, this is no esoteric surgical content, join us as Nick, Cale and Bashar get comfy with the weirder parts of the periodic table and how they apply to less common deficiencies or toxicities in haematology. Look we’ll be honest with you - this is pretty low yield listening but it was fun, and really isn’t that point at the end of the day. Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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