Episode #1
Mechanistic Drivers of Sjogren’s
Aug 17, 202617 minS0
<p>Sjogren's has long been reduced to its most visible symptoms, but the biology tells a more complex story. In this episode, Dr. Nancy Carteron walks through the immune mechanisms driving Sjogren's from the inside out, including the interplay between Type I interferon signaling and B-cell hyperactivity, how germinal center structures in the salivary glands fuel ongoing autoimmunity, and why BAFF dysregulation may be a critical and underappreciated therapeutic target.</p> <p>Nancy also addresses the systemic reach of the disease into the lungs, nervous system, and beyond, and explains why a handful of routine lab values can help clinicians...
