Doctors Take the Mic

Podcasts about medicine, health, wellness, society and what's new in medicine.Weekly podcasts about health and society

Doctors Take the Mic is a health podcast hosted by Gloria Wu, MD, with 203 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

Gloria Wu, MD hosts Doctors Take the Mic, a health show with 203 episodes published.

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  Episode #31

  Reversing Hormone Fear

  Aug 20, 202610 minS10

  For two decades, menopausal hormone therapy has carried the shadow of the 2002 Women's Health Initiative panic. In this episode, Dr. Wu and Darren unpack a landmark nationwide Danish cohort study, "Menopausal hormone therapy and long term mortality: nationwide, register based cohort study," by Anders Pretzmann Mikkelsen, Thomas Bergholt, Øjvind Lidegaard, and Nikolai Madrid Scheller, published in The BMJ (BMJ 2026;392:e085998). Drawing on data from more than 876,000 women followed for a median of 14.3 years, the study found no increased mortality risk associated with hormone therapy overall, a striking 27–34% lower mortality hazard among women who used it after surgical menopause, and a clear survival advantage for transdermal formulations over oral ones. Tune in for a data-driven conversation about why the original WHI trial misled a generation of doctors and patients, what the new numbers actually show, and what current clinical guidelines now recommend.

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  Episode #30

  AI, Bias, and Diabetes: What Six New ENDO 2026 Posters Found

  Jun 18, 202631 minS10

  Dr. Gloria Wu and Darren walk through six research posters their team presented at ENDO 2026, the Endocrine Society's annual meeting, exploring AI and diabetes patient education. They start with two posters showing how a physician-built AI chatbot, restricted to trusted medical sources, can deliver clear and accurate health guidance that real patients found genuinely helpful. Then they dig into four posters that put commercial AI models like ChatGPT, Gemini, Grok, and Claude to the test, revealing that these tools often give different medical advice — including different reading levels, specialist referrals, and treatment recommendations — depending on a patient's race and gender. The episode makes the case that AI can be a powerful tool for patient education, but only when clinicians are actively involved in building and checking it. References: Lin, T., Gonzalez, D., Hsiung, Y. Y., & Wu, G. (2026). Can clinicians build acceptable AI tools for diabetes education? [Abstract]. Journal of the Endocrine Society, 10 (Suppl_1). Poster presentation, Endocrine Society, Chicago, June 15, 2026. Paliath-Pathiyal, H., Wu, G., Tewari, S., Toram, V., Toram, R., Gonzalez, D., Lin, T., & Tarkoff, J. (2026). Racial and gender bias in artificial intelligence guidance for pediatric type two diabetes [Abstract]. Journal of the Endocrine Society, 10 (Suppl_1). Poster presentation, Endocrine Society, Chicago, June 13, 2026. Paliath-Pathiyal, H., Wu, G., Wang, M., Toram, V., Gonzalez, D., & Tarkoff, J. (2026). Race and gender differences in large language model responses for adolescents with newly diagnosed type 1 diabetes [Abstract]. Journal of the Endocrine Society, 10 (Suppl_1). Poster presentation, Endocrine Society, Chicago, June 14, 2026. Lin, T., Gonzalez, D., Toram, R., & Paliath-Pathiyal, H., Wu, G. (2026). Can MDs create a LLM-chatbot for diabetes patient education? [Abstract]. Journal of the Endocrine Society, 10 (Suppl_1). Poster presentation, Endocrine Society, Chicago, June 13, 2026. Tewari, S., Wu, G., Oggi, H., Paliath-Pathiyal, H., Wang, M., Toram, R., Tsay, J., Hsiung, Y. Y., & Tewari, S. (2026). Large language models, Asians, and the metabolic syndrome [Abstract]. Journal of the Endocrine Society, 10 (Suppl_1). Poster presentation, Endocrine Society, Chicago, June 2026. Tsay, J., Hsiung, Y. Y., Oggi, H., Chim, I., Mansubi, N., Wang, M., & Wu, G. (2026). LLM for adolescent T1DM: Clinical gaps and gender bias [Abstract]. Journal of the Endocrine Society, 10 (Suppl_1). Poster presentation, Endocrine Society, Chicago, June 2026.

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  Episode #26

  Light Pollution and Pollen

  Jun 11, 202619 minS10

  In this episode, Dr. Wu and co-host Darren Gonzalez, joined by Jordan Tsay and Kosuke Kimura, explore a striking paradox at the intersection of urban lighting, plant biology, and allergic disease, drawing on Artificial Light at Night Extends Pollen Season and Elevates Allergen Exposure , published in PNAS Nexus in 2026 by Brandt Geist, Lin Meng, Daniel S. W. Katz, Huidong Li, Franz Hölker, and Qian Xiao, a team led from Vanderbilt University. Pairing a decade of pollen counts with satellite measures of nighttime light across the Northeastern U.S., the researchers found that artificial light extends the pollen season at both ends — up to 130 additional pollen days a year between the darkest and brightest sites — while "severe" pollen days rose to 27 percent of the season versus 17 percent in darker areas. The effect may operate through two pathways at once: the same light that prolongs flowering in ragweed and London plane trees also disrupts the circadian regulation of allergic inflammation in humans. The loss of the night sky may be the most familiar consequence of urban lighting, but it may not be the most significant. References: Zaraska, M. (2026, June 4). Bright city lights might be making your allergies worse. The New York Times. https://www.nytimes.com/ 2026/06/04/climate/urban- light-pollution-pollen- allergies.html?eafs_enabled= false Geist, B., Meng, L., Katz, D. S. W., Li, H., Hölker, F., & Xiao, Q. (2026). Artificial light at night extends pollen season and elevates allergen exposure. PNAS Nexus , 5 (1), Article pgaf405. https://doi.org/10.1093/pnasnexus/pgaf405

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  Episode #25

  Diabetes and Smell

  Jun 10, 202611 minS10

  In this episode, Dr. Wu and co-host Darren Gonzalez explore a striking paradox at the intersection of diabetes and neuroscience, drawing on Type 2 Diabetes Impairs Odour Detection, Olfactory Memory and Olfactory Neuroplasticity; Effects Partly Reversed by the DPP-4 Inhibitor Linagliptin , published in Acta Neuropathologica Communications in 2018 by Grazyna Lietzau, William Davidsson, Claes-Göran Östenson, Fausto Chiazza, David Nathanson, Hiranya Pintana, Josefin Skogsberg, Thomas Klein, Thomas Nyström, Vladimer Darsalia, and Cesare Patrone of Karolinska Institutet in Stockholm. Using a lean diabetic rat model, the researchers showed that type 2 diabetes causes a 50 percent collapse in olfactory neurogenesis, disables the brain's scent-regulating interneurons, and creates a 52 percent backlog of stalled memory cells in the piriform cortex — and that while a common diabetes drug beautifully rebuilt the cellular architecture, the rats still could not smell a thing.

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  Episode #24

  Hidden Smell Loss in Kidney Disease and Diabetes

  Jun 9, 202613 minS10

  In this episode, Dr. Wu and co-host Darren Gonzalez unpack a striking finding from Odor Olfactory Dysfunction in Chronic Kidney Disease and Diabetes Mellitus and Its Association with Nutritional Factors , published in the Caspian Journal of Internal Medicine in 2025 by Kamyar Iravani, Aida Doostkam, Jamshid Roozbeh, Leila Malekmakan, Seyed Reza Kasaee, and Amir Soltaniesmaeili of Shiraz University of Medical Sciences in Iran. Over half of CKD patients and nearly 40 percent of diabetic patients had measurable smell loss — yet most had no idea. Dr. Wu breaks down the two completely different biological mechanisms driving olfactory damage in each disease, explains the counterintuitive LDL cholesterol finding, and makes the case for why a simple scratch-and-sniff test should become standard clinical practice for anyone living with chronic kidney disease or diabetes.

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