
Executive Insights for Life Sciences Innovators
Pawel Krysiak | Jaya Biosciences - Gene Therapy for Neurodegeneration
In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Pawel Krysiak, President & CEO of Jaya Biosciences. Pawel discusses JayaBio’s work to develop CNS-directed gene therapies for genetically defined neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and frontotemporal dementia. The conversation explores JayaBio’s focus on lysosomal enzyme gene heterozygosity and how this approach may help identify patient subpopulations within diseases historically treated as broad, heterogeneous conditions. Pawel also shares perspective from more than 20 years across neurodegeneration, oncology, rare diseases, commercialization, market access, and company building, including lessons from orphan drug launches and the challenge of advancing differentiated science toward clinical development. This episode was streamed live on YouTube on June 29, 2026 . Learn more at genecoda.com .

