
Episode #24
Nitric Oxide, the Oral Microbiome & Whole-Body Health (with Dr. Shawn J. Green, MyFitStrip)
In this episode of Functional Roots, hygienists Amanda and Heather interview Dr. Shawn J. Green—nitric oxide scientist, inventor, and founder of MyFitStrip—about how oral health connects to whole-body wellness through nitric oxide biology and the oral microbiome. Dr. Green shares his early Walter Reed research showing immune cells generate nitric oxide via iNOS to defend against intracellular pathogens like malaria, then explains why dental professionals should care: supporting nitrate-reducing “good” bacteria can boost local nitric oxide, suppress nitric-oxide–sensitive pathogens like Porphyromonas gingivalis, shift oral pH, and support systemic nitric oxide bioavailability. They discuss prebiotic nitrate strategies (diet and slow-release lozenges/gums), ingredient choices like vitamin C, xylitol, and zinc, concerns about sterilizing antimicrobials and mouthwash, the role of potassium nitrate toothpaste, nitrate vs nitrite, and how MyFitStrip test strips measure salivary nitrate and nitrite as lifestyle feedback.00:00 Welcome to Functional Roots00:38 Meet Dr Shawn Green04:11 Early Nitric Oxide Research08:20 iNOS and Immune Defense11:44 Why Hygienists Should Care13:44 Prebiotic Nitrate and Oral Microbiome21:55 Bristle Scores and pH Shifts28:10 Responders and Microbiome Resilience33:22 Vitamin C Xylitol Zinc Synergy39:05 Potassium Nitrate Toothpaste Debate47:40 Ingredient Label Red Flags48:51 Zinc and Oral Benefits50:44 Nitrate vs Nitrite Explained55:24 Beets Aren’t the Best01:00:49 MyFit Strip Basics01:03:54 Reading the Two Columns01:11:02 Do Inflammation Strips Change01:12:59 Key Takeaways Recap01:16:47 Industry Pushback and Shift01:20:06 Dentistry as Preventive Cardiology01:21:33 Where to Find MyFit Strip01:23:23 Final Thanks and Wrap






