High-Impact Growth

A podcast for social entrepreneurs, global development funders, nonprofit leaders and anyone grappling with the challenge of how to build solutions that are both immensely impactful and also achieve high-growth. Join Dimagi CEO and co-founder, Jonathan Jackson, along with co-host Amie Vaccaro as we unpack learnings from 20 years building digital solutions for global health and development, explore barriers to and opportunities for high-impact growth, and speak with industry leaders from around the world. Find us at: https://dimagi.com/podcast/

High-Impact Growth is a technology podcast hosted by Dimagi, with 87 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

Dimagi hosts High-Impact Growth, a technology show with 87 episodes published.

Our AI reads these to draft pitches. Use them as grounding for a pitch that cites a real guest and a specific topic.

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  Episode #88

  From Embracing Complexity to Solving the Right Problems

  Aug 18, 202646 minS1

  Could a funder deploy $100 million in global health tomorrow and know where every single dollar went? Dimagi CEO and co-founder Jonathan Jackson believes verified service delivery finally makes the answer yes. In this candid mid-2026 check-in, Jon joins co-host Amie Vaccaro, VP of CommCare Growth and Strategy, to unpack a year of profound change including why Dimagi retired its longtime value "embrace complexity for impact" in favor of "solving the right problems for impact," and what that shift reveals about affordability in a post-USAID funding landscape. Jon walks step-by-step through a single Connect-enabled home visit, from opt-in push notification to real-time payment, and shares the numbers behind the platform: over 1.5 million verified visits, 200+ local organizations expressing interest, and 80 cents of every dollar reaching frontline workers, local organizations, and commodities. The conversation also explores how AI is putting program design directly into the hands of local organizations, automating roles, not people. As Jon puts it: "When you do a better job today, the system knows it and can offer you even more work tomorrow." Related Resources: Dimagi Connect – Dimagi's verified service delivery platform connecting funders with local organizations and frontline workers. CommCare by Dimagi – The open-source platform for frontline workers that Connect is built on, with a quarter million active users worldwide. GiveWell – The evidence-based charity evaluator whose request for information on post-market malaria rapid diagnostic test surveillance inspired Dimagi's AI-built Connect pilot. Steel Foundation for Hope – An early flagship funder that Amie credits with seeing Connect's potential. Kevin Starr episode of High-Impact Growth – https://dimagi.com/podcast/funders-power-to-change-the-system/ Eric Ries episode of High-Impact Growth – https://dimagi.com/podcast/podcast-eric-ries-good-companies-go-bad/ Kikapu Gardens field visit video – https://drive.google.com/file/d/1MLGVhiA0YCt_NpjuF4Gveu1s3kwygD7-/view Sign up to our newsletter⁠ , and stay informed of Dimagi’s work We are on social media - follow us for the latest from Dimagi: ⁠LinkedIn⁠ , ⁠Twitter⁠ , ⁠Facebook⁠ ⁠⁠, ⁠Youtube⁠ ⁠⁠⁠ If you enjoy this show, please leave us a 5-Star Review and share your favorite episodes with friends. Hosts: ⁠ Jonathan Jackson⁠ and ⁠Amie Vaccaro

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  Episode #87

  Eric Ries on Why Good Companies Go Bad

  Aug 7, 202656 minS1

  What does it really mean to make a profit — and why do so many mission-driven companies eventually betray the very things that made them great? In this episode, Eric Ries, creator of The Lean Startup and founder of the Long-Term Stock Exchange, joins Amie Vaccaro and Jonathan Jackson to discuss his new book Incorruptible: Why Good Companies Go Bad and How Great Companies Stay Great . Eric dismantles the conventional definition of profit and offers a radical replacement — profit as the maximization of human flourishing — then explains "financial gravity," the unconscious pull that bends organizations toward the values of whoever holds the money, whether investors or donors. Through the origin stories of Costco and Novo Nordisk, he shows how "mission lock" structures protected both companies — in Novo Nordisk's case, preserving the research that became Ozempic and creating over $500 billion in shareholder value. The conversation closes with practical power for everyone else: a "no-courage activism" question any job candidate can ask, and why every transaction you make transmits your values. As Eric puts it: "You're not stuck in traffic — you are traffic." Related Resources: https://theleanstartup.com/ ⁠ – Eric's foundational methodology and NYT bestseller on entrepreneurship and continuous innovation. Long-Term Stock Exchange (LTSE) – The stock exchange Eric founded to support companies built for long-term value creation. Answer.AI – The AI R&D lab founded by Eric Ries and Jeremy Howard. B Lab / B Corp Certification – The certification body behind B Corps; Dimagi was the first B Corp/PBC in Massachusetts, referenced in the conversation. Novo Nordisk Foundation – The mission-guardian foundation whose governance structure blocked the merger that would have killed GLP-1 research. Sign up to our newsletter⁠ , and stay informed of Dimagi’s work We are on social media - follow us for the latest from Dimagi: ⁠LinkedIn⁠ , ⁠Twitter⁠ , ⁠Facebook⁠ ⁠⁠, ⁠Youtube⁠ ⁠⁠⁠ If you enjoy this show, please leave us a 5-Star Review and share your favorite episodes with friends. Hosts: ⁠ Jonathan Jackson⁠ and ⁠Amie Vaccaro

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  Episode #86

  The Last Mile of Family Planning: Lessons from Lafiya in Nigeria

  Jul 29, 202643 minS1

  In a single program area in northern Nigeria, contraceptive use climbed from 2% to over 70%. This change wasn't caused by a new technology, but happened because of one new strategy: centering trust. In this episode, Jonathan Jackson and Amie Vaccaro sit down with Klau Pakos, CEO and co-founder of Lafiya, to unpack how their organization closes the "last mile" gap in family planning in some of the hardest-to-reach communities in Northern Nigeria. Women in these communities often already know about contraception, but too often travel hours to a clinic only to be turned away empty-handed. Lafiya's answer is the Lafiya Sisters — trusted local health workers who bring counseling and self-injectable contraceptives directly into communities. Klau shares the visceral reality of women facing extreme maternal mortality risks, walks through how Lafiya became a true partner to the government rather than a vendor with a fixed model, and explains why they resist the pull of shiny new technology until it's proven necessary. As they put it, family planning "brings the foundation for everything else", creating ripple effects across health, income, and autonomy that data alone can't fully capture. A candid, practical conversation for anyone trying to scale impact alongside government systems. Related Resources: Lafiya – Klau's organization, which trains local "Lafiya Sisters" to deliver family planning counseling and self-injectable contraceptives to underserved communities in northern Nigeria. D-Prize – A seed funding organization that awards grants to entrepreneurs testing new business or charity models that distribute proven poverty-intervention technologies Charity Entrepreneurship – An incubator program that helps founders launch high-impact, cost-effective charities. Rethink Priorities: Cost-Effectiveness Analysis of Lafiya Nigeria – The independent modeling Klau references, estimating Lafiya's cost per DALY averted and per maternal life saved. Sayana Press (DMPA-SC) via Pfizer – An all-in-one, self-injectable contraceptive that lasts for three months and is optimized for low-resource environments due to its lack of a cold chain requirement. https://www.fp2030.org/ - A global partnership dedicated to advancing rights-based family planning, which the Nigerian government has contributed to for over a decade. Sign up to our newsletter⁠ , and stay informed of Dimagi’s work We are on social media - follow us for the latest from Dimagi: ⁠LinkedIn⁠ , ⁠Twitter⁠ , ⁠Facebook⁠ ⁠⁠, ⁠Youtube⁠ ⁠⁠⁠ If you enjoy this show, please leave us a 5-Star Review and share your favorite episodes with friends. Hosts: ⁠ Jonathan Jackson⁠ and ⁠Amie Vaccaro

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  Episode #85

  Why Development Needs More Innovation, Not Less with DIV Fund

  Jul 23, 202650 minS1

  When USAID was dissolved, Sasha Gallant didn't let the work she'd spent years building disappear with it. As the former head of Development Innovation Ventures (DIV), USAID's evidence-driven innovation fund, Gallant watched stop-work orders freeze over 100 active awards overnight. Rather than let that portfolio die, she did two things: Helped mobilize more than $130 million to keep the most critical, life-saving USAID projects alive through an initiative called Project Resource Optimization , and Co-founded DIV as an independent nonprofit–the DIV Fund –to test and scale new, potentially cost-effective global development innovations. In this conversation with co-hosts Jonathan Jackson and Amie Vaccaro, Gallant unpacks why innovation funding in global development is chronically underfunded, how DIV evaluates ideas on evidence, cost-effectiveness, and potential for scale, and why the biggest wins are often "supremely unshiny": pedagogical tweaks, cheaper CPAP machines, smarter delivery models. She also grapples with a strange moment of dissonance: surviving deep funding cuts just as a new wave of AI-driven wealth approaches the sector. As she puts it, believing we've already found our best solutions is "basically giving up on human progress." For funders, innovators, and development leaders navigating a rapidly changing funding landscape, this episode offers thoughtful guidance on building a future where every dollar creates greater impact. Related Resources: DIV Fund – The independent nonprofit Sasha Gallant co-founded, continuing USAID's Development Innovation Ventures model of tiered, evidence-driven innovation grants. Project Resource Optimization (PRO) – The initiative (hosted by the Center for Global Development) that Gallant helped launch to triage and match donors to the most cost-effective USAID programs left without funding. GiveWell – The charity evaluator referenced for its rigorously vetted "best buy" list of cost-effective global health and development programs. Sign up to our newsletter⁠ , and stay informed of Dimagi’s work We are on social media - follow us for the latest from Dimagi: ⁠LinkedIn⁠ , ⁠Twitter⁠ , ⁠Facebook⁠ ⁠⁠, ⁠Youtube⁠ ⁠⁠⁠ If you enjoy this show, please leave us a 5-Star Review and share your favorite episodes with friends. Hosts: ⁠ Jonathan Jackson⁠ and ⁠Amie Vaccaro

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  Episode #84

  Who Actually Owns This? Naming What's Broken with Nithya Ramanathan

  Jun 26, 202649 minS1

  What does it actually take for a country, government, or community to truly own a technology or an outcome? In this fast-paced and candid episode of High-Impact Growth, Dimagi CEO Jonathan Jackson and co-host Amie Vaccaro welcome back Nithya Ramanathan, CEO and co-founder of Nexleaf Analytics. Moving past polite sector rhetoric, Nithya and Jonathan break down why so many well-intentioned global health initiatives end up in "equipment graveyards" due to a broken "donor-to-hope" value chain. Grounded in her recent Stanford Social Innovation Review piece on country ownership, Nithya unpacks the three critical ingredients of true ownership—financial transaction, genuine control, and intrinsic pride—and advocates for a drastic shift: flipping the historical 80/20 investment split to focus heavily on human operational systems rather than chasing technical perfection. Featuring real-world insights from a recent cross-country ministry workshop on vaccine cold chains, this episode offers an honest look at the iterative dance between technology and policy. The conversation doesn't offer tidy answers, but it pushes the critical questions. Related Resources: https://ssir.org/articles/entry/scaling-global-health-innovations Nithya Ramanathan, Nelima Otipa, and Hosea Kintu lay out a framework for moving from government partnership to country ownership in global health innovation. Referenced directly in the episode. https://www.nexleaf.org/ A non-profit social enterprise co-founded by Nithya Ramanathan that uses data and technology to improve global health systems, particularly vaccine cold chains. https://www.gavi.org/ A global health partnership that co-supported the multi-year vaccine cold chain and operational maintenance initiatives discussed in the episode. Kevin Starr / Mulago Foundation Thought leader behind the concept of "Coke bottle philanthropy" cited by Nithya — the false notion that a single scalable solution can be handed to governments like a product off a shelf. https://dimagi.com/commcare/ Dimagi’s SaaS product designed to support frontline workers and track community health outcomes at scale. Sign up to our newsletter⁠ , and stay informed of Dimagi’s work We are on social media - follow us for the latest from Dimagi: ⁠LinkedIn⁠ , ⁠Twitter⁠ , ⁠Facebook⁠ ⁠⁠, ⁠Youtube⁠ ⁠⁠⁠ If you enjoy this show, please leave us a 5-Star Review and share your favorite episodes with friends. Hosts: ⁠ Jonathan Jackson⁠ and ⁠Amie Vaccaro

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