Hump Day Hormones

This is a podcast about all things hormones! Dr. Jill Jennings and Kortney Spann, APRN are so excited to share their knowledge and expertise about menopause, perimenopause, and hormone imbalances.

Hump Day Hormones is a education podcast hosted by Unknown Host, with 0 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

Unknown Host hosts Hump Day Hormones, a education show with 0 episodes published.

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  Episode #82

  I Can't Take Progesterone... Now What? What Is Up With Progesterone Intolerance

  Aug 19, 202656 minS2

  Progesterone can be incredibly helpful for some women. It can support sleep, calm the nervous system, regulate bleeding, and play an important role in hormone therapy. But for some women, taking progesterone can bring on anxiety, depression, fatigue, dizziness, brain fog, bloating, or that frustrating feeling of simply not feeling like themselves. So what is actually happening? In Episode 82, we’re diving into progesterone intolerance, why some women can have such a different response to the same hormone, and what options exist when oral micronized progesterone simply doesn’t work for you. In this episode, we break down: • What progesterone intolerance actually is and how it differs from progestin intolerance • Why allopregnanolone and the GABA A receptor may play a role in how women respond to progesterone • Why some women tolerate their own natural progesterone but struggle with oral progesterone • How the timing, dose, and route of progesterone can change your experience • What other options may provide endometrial protection when oral progesterone isn't tolerated • Why progesterone creams may not provide adequate uterine protection • How options like an IUD, different progestins, or Duavee may fit into the conversation One of the biggest takeaways from this episode is that “I can’t tolerate progesterone” doesn’t mean the conversation is over. Your response to hormones is individual, and the goal is to find a safe, effective treatment plan that you can actually live with. If progesterone has ever made you feel worse instead of better, this is an episode you’ll want to hear. Share this with a woman who has ever wondered why progesterone makes her feel awful. Progesterone Intolerance | Progesterone Therapy | Hormone Replacement Therapy | Menopause Care | Micronized Progesterone | Hormone Health | Perimenopause | Women's Health #HumpDayHormones #Progesterone #ProgesteroneIntolerance #HormoneReplacementTherapy #Menopause #Perimenopause #HormoneHealth #WomensHealth #MicronizedProgesterone #MenopauseEducation

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  Episode #79

  Should We Check Estradiol Levels? Why Your Number Might Matter More Than You Think

  Jul 22, 202648 minS2

  "Should your estradiol level be checked while you're on hormone therapy?" "Or do your symptoms tell us everything we need to know?" It's one of the biggest debates in menopause medicine. Some providers say blood levels don't matter. Others want to see your estradiol above a certain number. So... who's right? In this episode, we unpack what the research actually says and explain why the answer depends on what you're trying to accomplish. While symptoms remain the best guide for relieving hot flashes and night sweats, optimizing long term health may be a different conversation. In this episode, we break down: • Why routine estradiol testing isn't recommended for every woman on hormone therapy • What estradiol levels may tell us about bone health and osteoporosis prevention • How estrogen supports cardiovascular health, healthy blood vessels, and cholesterol • The connection between estradiol, insulin resistance, and metabolic health • What we know, and don't yet know, about estrogen and brain health after menopause • Why treating symptoms and optimizing long term health aren't always the same goal • How to think about estradiol numbers without chasing a "perfect" lab value The biggest takeaway? We don't treat lab numbers, we treat women. Hormone therapy should always be individualized, using both symptoms and the best available evidence to support long term health. Share this episode with someone navigating menopause or a healthcare provider who wants to stay up to date on the evolving science of hormone therapy. #HumpDayHormones #Menopause #Estradiol #HormoneReplacementTherapy #HormoneHealth #BoneHealth #HeartHealth #Women'sHealth #MenopauseEducation #HealthyAging

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  Episode #78

  GLP-1s & Breast Cancer: What the New Research Really Says

  Jul 15, 202639 minS2

  A new Penn Medicine study is making headlines after researchers found that women taking GLP-1 medications had about 30% lower odds of being diagnosed with breast cancer compared to similar women who were not taking these medications. So what does that actually mean? In this episode, we separate the headlines from the science and explain why researchers are excited, while also discussing what we still don't know. In this episode, we break down: • What the new Penn Medicine breast cancer study actually found • Why a 30% lower risk does not mean 30 out of 100 women avoided breast cancer • How obesity, insulin resistance, inflammation, and estrogen influence breast cancer risk • The biologic reasons GLP-1 medications may help reduce cancer risk • The important limitations of this research and why it does not prove cause and effect • What these findings could mean for women with obesity, insulin resistance, or a family history of breast cancer The most exciting part of this research isn't that we suddenly have a new breast cancer prevention drug. It's that improving metabolic health may impact far more than the number on the scale. As always, we'll discuss what the evidence supports today, what questions remain unanswered, and where the research is headed next. Share this with someone who's been seeing the headlines and wondering what they really mean. #HumpDayHormones #GLP1 #BreastCancerResearch #Semaglutide #Tirzepatide #WomensHealth #HormoneHealth #MetabolicHealth #BreastCancerAwareness #MedicalResearch

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  Episode #77

  PCOS Is Getting a New Name - And It’s About Time - PMOS

  Jul 1, 202644 minS2

  After nearly 100 years, one of the most common hormone disorders affecting women has officially been renamed. Following a 14 year international effort involving more than 22,000 patients, researchers, and medical experts, Polycystic Ovary Syndrome (PCOS) is now being called Polyendocrine Metabolic Ovarian Syndrome (PMOS). Why does that matter? Because the new name finally reflects what science has been telling us for years, this is a whole body hormonal and metabolic condition, not simply an ovarian disorder. In this episode, we break down: • Why PCOS was officially renamed PMOS and what prompted the historic change • What the new name tells us about hormones, insulin resistance, and metabolism • Why up to 70% of women with PMOS remain undiagnosed • The four different types of PMOS patients we commonly see in clinic • The long term health risks that extend far beyond fertility and irregular periods • Why treatment needs to focus on both hormone balance and metabolic health One of the biggest takeaways from this episode is that you probably know someone living with PMOS, whether they realize it or not. The condition affects up to 1 in 7 women of reproductive age, making it one of the most common endocrine disorders in women. Understanding the new name isn't just about changing terminology. It's about changing the conversation, improving diagnosis, reducing stigma, and helping women receive the care they deserve. Share this with a friend because chances are... you have a friend with PMOS. #HumpDayHormones #PMOS #PCOS #HormoneHealth #InsulinResistance #WomensHealth #MetabolicHealth #EndocrineHealth #HormoneEducation #WomensWellness

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  Episode #76

  GLP-1 Summer School: The Questions We’re Getting Asked All Summer Long

  Jun 24, 202656 minS2

  This week we're heading back to school, GLP-1 Summer School, to answer the questions we're getting asked every single day in clinic. A few years ago, hardly anyone had heard of medications like Ozempic, Wegovy, Mounjaro, and Zepbound. Now they're everywhere. Some people think they're a miracle. Others think they're dangerous. Most women are simply trying to sort through the noise and understand what is actually true. In this episode, we break down: • How GLP-1 medications actually work in the body • What realistic weight loss looks like with semaglutide and tirzepatide • Why these medications are about much more than weight loss • Whether you'll gain weight back after stopping and how to transition off successfully • The truth about muscle loss, hair loss, and "Ozempic face" • How GLP-1 therapy and hormone replacement therapy may work together • What patients should know about compounded medications • Why retatrutide is generating so much excitement for the future of obesity medicine We also discuss one of the biggest misconceptions surrounding GLP-1 therapy: the idea that the medication is the entire treatment plan. The medication may open the door, but long term success still depends on nutrition, muscle preservation, sleep, stress management, hormone health, and sustainable habits. This conversation is designed to help you understand the science, separate fact from fiction, and make sense of one of the fastest moving areas in medicine today. Share this with the friend who keeps texting you GLP-1 questions. #HumpDayHormones #GLP1 #Semaglutide #Tirzepatide #Ozempic #Wegovy #Zepbound #Mounjaro #MetabolicHealth #WeightLossMedicine #HormoneHealth #WomensHealth

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