Episode #62
62. GLP-1s: What They Do, What They Don’t, and What You Need to Know
GLP-1 medications have become one of the biggest conversations in weight loss, and Lisa believes the discussion needs more nuance than simply deciding whether they are “good” or “bad.” In this episode, Lisa breaks down what GLP-1 actually means, how the hormone works naturally inside the body, and why medications such as Ozempic, Wegovy, Mounjaro, and others can reduce appetite, slow stomach emptying, and support blood sugar regulation. She also walks through common side effects, including nausea, constipation, fatigue, digestive changes, and loss of lean muscle mass. But this conversation goes beyond medication. Lisa explains how protein, fiber, exercise, insulin sensitivity, hunger hormones, and gut health all play a role in appetite and body composition. She also challenges listeners to ask a deeper question: what led to the weight gain, fatigue, cravings, or metabolic struggles in the first place? This episode is not about shaming anyone for using a GLP-1. It is about understanding your options, becoming an active participant in your health, and recognizing that sustainable change still requires attention to the habits, food, and lifestyle supporting your body every day. In this episode, Lisa explores: What GLP-1 is and how your body naturally produces it How GLP-1 medications affect appetite, digestion, and blood sugar Common side effects and concerns around muscle loss and digestive health Why protein, fiber, movement, and insulin sensitivity still matter The connection between gut health, hunger hormones, and sustainable weight management Key Moments 03:38 – How GLP-1 interacts with hunger hormones, appetite, and insulin sensitivity 08:32 – The most common GLP-1 medications and potential side effects 18:10 – How protein, fiber, and real food can support your body’s own GLP-1 response 22:52 – Why Lisa believes getting to the root of weight gain matters 27:47 – Ozempic, Wegovy, Mounjaro, and the differences between GLP-1 medications Ready to Heal Your Gut? If you’re ready to stop guessing and finally understand which foods work for your body, Lisa’s Simply the Best program walks you through her proven step-by-step gut healing method. Learn more here: https://pages.lisagarrettnutrition.com/simply-the-best FREE GUT ANALYSIS CALL Schedule your free gut analysis call with me! CONNECT WITH LISA Instagram: @lisagarrettnutrition Website: https://www.lisagarrettnutrition.com/ SUPPORT LET’S TALK SH*T ✨ Love what you’re hearing? Please subscribe, rate, and review Let’s Talk Sh*t! Your support helps spread the light to more listeners. Share this episode with a friend or tag it in your IG stories. Don’t forget to follow along on Instagram @lisagarrettnutrition for more inspiration.
