LONGEVITY with Nathalie Niddam

LONGEVITY with Nathalie Niddam is your go-to podcast for diving deep into the science and practices for increasing your longevity and healthspan. This podcast covers topics from nutrition, biohacking, longevity, peptides, bioregulators, cutting edge research, health technology and more! Nathalie Niddam is a certified nutritionist, as well as a epigenetics and human potential coach.

LONGEVITY with Nathalie Niddam is a health podcast hosted by Nathalie Niddam, with 460 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

Nathalie Niddam hosts LONGEVITY with Nathalie Niddam, a health show with 460 episodes published.

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  LONGEVITY with Nathalie Niddam

  #465: Personalizing GLP-1 Medications: The Role of Genetics in Weight Loss and Side Effects With Noura Abul-Husn M.D. Ph.D

  Aug 18, 20261h 22m

  Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I’m joined by the incredible Dr. Nora Abdul-Hussein, a physician-scientist, medical geneticist, and one of the leading voices in the field of genomic medicine. In this episode, Dr. Abdul-Hussein and I dig into a huge question—why do two people taking the exact same GLP-1 medication have such wildly different results, from weight loss to side effect profiles? She shares her unique path from internal medicine to cutting-edge population genomics, and how her work at 23andMe is beginning to answer some of medicine’s toughest puzzles. Episode Timestamps: Introduction: podcast focus on genetics, peptides, and longevity ... 00:00:00 Dr. Nora Abdul-Hussein’s background and journey in genomic medicine ... 00:07:01 Prevention and population-scale genetics ... 00:08:06 Power of genetic insights for personal lifestyle choices ... 00:14:40 Barriers to adopting genetics in clinical practice ... 00:16:41 Pharmacogenomics and the move toward personalized prescribing ... 00:17:21 Launching a large-scale study on GLP-1 genetics ... 00:19:41 Discovery: GLP-1 receptor gene variants linked to weight loss and nausea ... 00:22:40 Risk calculators and personalized expectations for GLP-1s ... 00:27:26 Broader genomics: diet, exercise, and response variability ... 00:28:24 Avoiding genetic determinism and emphasizing holistic care ... 00:29:29 Findings for tirzepatide and the GIP receptor ... 00:34:20 Population differences and ancestry’s impact on results ... 00:38:07 Is genetic information ready for prime time in GLP-1 therapy? ... 00:41:12 Clinical implications beyond “calories in, calories out” ... 00:43:01 GLP-1s: potential for non-weight related conditions ... 00:44:48 Personalized medicine: integrating genomics with other data ... 00:51:02 Reducing shame and embracing genes as tools for prevention ... 01:00:02 Genomic information as an empowering health strategy ... 01:01:30 Study insights and validation: self-reporting and sample diversity ... 01:05:40 Protecting privacy and building trust in genomics ... 01:13:32 Final thoughts: embrace your genes and use the data for healthspan ... 01:20:10 Where to learn more and wrap-up ... 01:21:18 Our Amazing Sponsors: Mitopure Gummies by Timeline – Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A—without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/NAT20 to get Mitopure starting at just $99 and save an additional 20% on your order. Manukora Honey – A delicious real-food source of prebiotics, Manukora's high-MGO Manuka honey helps support your gut microbiome, digestion, and immune health with just one teaspoon a day. Head to MANUKORA.com/NAT to save up to 31% plus receive $25 worth of free gifts with the Starter Kit. Just Thrive 90-Day Probiotic – A spore-based probiotic that survives stomach acid to arrive 100% alive in your gut, supporting better digestion, nutrient absorption, immunity, and less bloating. Start your first 90-day subscription today and you'll get a FREE 90-day supply of Digestive Bitters (a $90 value) to help optimize digestion and support healthy appetite regulation. Click HERE to learn more. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

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  LONGEVITY with Nathalie Niddam

  #464: Brain POWER: The Creatine Revolution, Exercise Snacks, and the Age of Energy | Dan Pardi

  Aug 14, 20261h 28m

  Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I’m joined by Dan Pardi, a pioneering researcher who has dedicated years to understanding sleep, performance, and—the real focus of today’s conversation—the science of human energy. Dan unpacks how modern life is quietly draining our brain’s battery, and why brain energy, not just the march of time, could be the hidden driver of longevity. We dive into why short “exercise snacks” can outperform marathon workouts for keeping your brain sharp, how chronic stress and relentless screen time undermine cognitive performance, and the surprising reasons creatine is fast becoming a game-changer for brain health, not just muscle building. Visit qualialife.com/nathalie and use code NATHALIE at checkout to save 15%. Episode Timestamps: Welcome and podcast introduction ... 00:00:00 Exercise snacks and their impact on cognitive performance ... 00:07:29 How modern stress and technology deplete brain energy ... 00:12:12 Environmental influences on sleep and energy ... 00:13:35 Redefining aging as an energy management issue ... 00:18:41 Muscle function, healthspan, and holistic longevity ... 00:21:53 Why the brain demands so much energy ... 00:25:30 Brain energy, cognitive decline, and examples like Alzheimer’s ... 00:29:07 Creatine’s history in sports and its cellular mechanism ... 00:35:38 Creatine’s cognitive benefits and how it reaches the brain ... 00:49:20 Sleep, adenosine, and energy maintenance ... 00:54:39 Creatine safety, kidney health, and gender differences ... 00:57:22 Bloating, body composition, and dosing myths ... 01:05:30 Why innovate creatine supplements and formulation upgrades ... 01:11:57 Micronization, magnesium, sodium, and absorption ... 01:13:00 Product testing and user experience ... 01:17:31 Future of brain energy science in longevity ... 01:22:45 Closing resources and medical disclaimer ... 01:28:47 Our Amazing Sponsors: Quantum Upgrade – A 24/7 quantum energy streaming service designed to support energy, focus, sleep, recovery, and a more balanced nervous system, backed by placebo-controlled research showing measurable improvements in stress-related brain activity and heart rate variability. Try it free for 15 days with no credit card required at quantumupgrade.io/NAT and use code NAT15. MitoQ Hormonal Metabolic Control – A targeted formula designed to support women through the hormonal and metabolic shifts of perimenopause and menopause, featuring S-Equol for healthy estrogen signaling, B. breve to support the gut-hormone connection, and chromium to help maintain healthy blood sugar balance. Head to MitoQ.com/nat and use code NAT10 to try it for yourself. Nature's Marvels Bioregulators by Profound Health - Natural bioregulators designed to support your body's own cellular communication and healthy aging, with targeted formulas for everything from brain and immune health to sleep and vitality. Visit profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

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  LONGEVITY with Nathalie Niddam

  #463: Reducing Breast Cancer Risks | HRT, Imaging, AI, BRCA, And GLP-1s With Dr. Elisa Port

  Aug 11, 20261h 9m

  Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I’m joined by Dr. Elisa Port, a trailblazing breast cancer surgeon and passionate advocate for women’s health. And the author of The Breast Advice In our conversation, Dr. Port traces her evolution from general surgery into breast surgery, sharing how the deeply collaborative decision-making with patients became her life’s calling. She gives an inside look at the optimism she found in this field—where advances in treatment have dramatically improved survival, offering hope and empowerment to countless women. Episode Timestamps: Welcome and show introduction ... 00:00:00 Path to breast surgery and collaborative care ... 00:05:45 Breast cancer, survival rates, and longevity factors ... 00:08:57 Impact of weight and lifestyle on recurrence risk ... 00:10:45 Dangers of information overload and misinformation ... 00:13:38 Evaluating new screening tests and lacking validation ... 00:16:17 Dense breast tissue and adjunctive screening ... 00:19:20 Galleri blood test and research gaps ... 00:22:08 Top lifestyle risk factors: weight and alcohol ... 00:23:32 Self-awareness and moderation with food and alcohol ... 00:27:45 GLP-1 medications and modern weight challenges ... 00:33:40 Compounding health issues from obesity ... 00:37:37 Long-term effects and benefits of weight loss drugs ... 00:40:09 Hormone replacement, risk, and individualized care ... 00:45:34 AI’s impact on breast imaging and detection ... 00:56:29 Physical and mental recovery after treatment ... 01:00:31 Future hopes: Cures and compliance ... 01:04:53 Summary of optimal breast health strategies ... 01:06:27 Our Amazing Sponsors: Wolverine by LVLUP Health – A peptide-based formula designed to support recovery, tissue repair, and musculoskeletal health, helping your body bounce back from workouts and everyday wear and tear. Head to lvluphealth.com and use code NAT for 15% off your order. MitoBlue by Wizard Sciences – A longevity-focused formula that combines pharmaceutical-grade methylene blue with NMN, PQQ, fisetin, and apigenin to support healthy mitochondria, cellular renewal, and healthy aging. Learn more at wizardsciences.com and use code NAT15 for 15% off. Vita Zero-Age Exosomes by Vitali Skincare — a regenerative “stacking” formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

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  LONGEVITY with Nathalie Niddam

  #462: STOP! Before Detoxing, Mold Doctor Says Do THIS First Or Risk Getting Worse With Dr. Jill Crista

  Aug 7, 20261h 24m

  Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I’m joined by Dr. Jill Crista, a pioneering voice in environmental medicine and a relentless detective when it comes to chronic, mysterious illness. In our conversation, Dr. Crista reveals how she uncovered the hidden world of mold and mycotoxins—not just as respiratory irritants, but as stealthy drivers of fatigue, brain fog, hormone disruption, and accelerated aging. She shares her early experiences working with “non-responders” in Lyme disease, and how uncovering toxic mold exposures transformed her entire understanding of whole-body health. Visit https://alighthealthformulas.com/nathalieniddam and code NATHALIENIDDAM Episode Timestamps: Podcast intro and host background ... 00:00:00 Peptides, bioregulators, and expert busting myths ... 00:02:10 Foundations of hydration and health ... 00:03:55 Mold as a multi-system problem, not just respiratory ... 00:06:12 Clinical questionnaires for mold and Lyme ... 00:12:02 Why mold illness is misunderstood ... 00:13:29 Mycotoxins vs. visible mold, and detection tips ... 00:14:17 Detox reactions and mold warning signs ... 00:22:46 Remediation challenges: “dead” mold ... 00:28:35 Different responses to mold exposure ... 00:29:43 Protective nutrition and the microbiome ... 00:31:19 Modern buildings and mold risks ... 00:33:35 Break the Mold: the 5-step approach ... 00:35:23 Pitfalls: skipping avoidance and early antifungals ... 00:35:38 Bioflavonoids and alternative binders ... 00:37:24 Aloe as a safe binder option ... 00:41:27 Mold recovery “crashes” and toxicity ... 00:42:58 Managing exposure when you can’t remediate ... 00:45:19 Long COVID and its overlap with mold ... 00:50:43 Essential oils and neuroinflammation support ... 01:04:08 Mold, accelerated aging, and healthspan ... 01:07:03 When to suspect mold in longevity “non-responders” ... 01:09:44 Key questions, testing, and early action steps ... 01:10:23 Hope, healing, and the importance of optimism ... 01:16:31 Our Amazing Sponsors: Bioregulators & Peptides Summit by DrTalks – Cut through the confusion around peptides and bioregulators with free expert-led sessions covering healthy aging, metabolism, recovery, fasting, and the latest science in a practical, easy-to-understand way. Register for free today at https://drtalks.com/summits/NAT. Electrolyze by BEAM Minerals - Electrolyze is a plant-based fulvic mineral formula that delivers a full spectrum of highly bioavailable trace minerals and electrolytes to support hydration, nutrient delivery, and cellular energy. Head to beamminerals.com/NAT20, use code NAT20, and get 20% off your first order. Mitopure Gummies by Timeline – Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A—without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/nat20 to get Mitopure starting at just $99 and save an additional 20% on your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

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  LONGEVITY with Nathalie Niddam

  #461:Why Only 8 Proven Interventions Work | Extend LIFE & Healthspan With Science Not Hype With Dr. Bill Lawrence

  Aug 4, 20261h 50m

  Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/. Today, I’m joined by Dr. Bill Lawrence, a leading researcher in longevity and pioneer in clinical studies on peptide bioregulators. Over the past eight years, Dr. Lawrence has dedicated himself to asking the big questions in longevity science: Do these interventions really work, and which strategies actually move the needle when it comes to living longer, healthier lives? Where to find Bioregulators: Visit Profound Health and use code NAT15 for 15% off your first order. Previous Episodes: #394 How Bioregulator Peptides HALVE Mortality: Telomere Reversal, Organs REGENERATED & the 8-Year Experiment With Dr. Bill Lawrence #256: Dr. Bill Lawrence: Bioregulator Peptides, New Insights on Aging, DNA Repair Mechanisms & the Impact of Stress on Telomere Length Dr Bill Lawrence: Reversing Aging PART 2 Bioregulator Peptides Effect on DNA Methylation Clinical Trial Episode Timestamps: Welcome and podcast introduction ... 00:00:00 Bioregulators: sourcing and beginner guidance ... 00:03:37 Defining hope, hype, and science in longevity ... 00:09:02 Framework for evidence-based interventions ... 00:11:08 Lifespan, healthspan, and longevity distinctions ... 00:19:31 Animal studies vs. human longevity research ... 00:27:51 Recognizing hype and influencer marketing ... 00:33:33 Experimental therapies: gene editing & reprogramming ... 00:36:06 GLP-1 drugs and healthspan evidence ... 00:41:03 Proven criteria for legitimate longevity interventions ... 00:46:03 Mortality risk reduction: sleep, lifestyle, and relationships ... 00:47:47 Evidence ladder: from mice to human studies ... 00:53:13 Peptide bioregulators: research history and mechanisms ... 01:01:19 Organ regeneration and biological age reversal ... 01:21:20 Epigenetic age, pace of aging, and case studies ... 01:34:00 Our Amazing Sponsors: C.A.R.E. Mitochondrial Moisturizer Young Goose – An upgraded cellular skincare formula featuring Methylene Blue and Liposomal Creatine to support mitochondrial function, skin barrier health, and resilient, hydrated skin. Click HERE and use code NAT10 to save on C.A.R.E. Mitochondrial Moisturizer. NEW Magnesium Breakthrough Advanced 10 by BIOptimizers – A magnesium formula featuring 10 bioavailable forms of magnesium, plus active vitamin B6 and ionic trace minerals, designed to support sleep, recovery, stress, and metabolic health. Visit bioptimizers.com/bionat and use code BIONAT for 15% off, exclusive bonuses, and free shipping on select orders. Grass-Fed Whey by Puori - A third-party tested, grass-fed whey protein delivering 21g of protein per serving, with every batch tested for over 200 contaminants and results available via a QR code for complete transparency. Head to puori.com/NAT20 and use code NAT20 to get 32% off your first subscription order, plus a free premium shaker bottle. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Original Instagram Backup Instagram Dr. Bill Lawrence Episode

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