
Episode #53
GLP-1 Weight Loss and Your Face Why Facial Volume Changes and What You Can Do About It
Significant weight loss can transform your health and confidence—but it can also create unexpected changes in your face. In this episode of Smile & Aesthetics, Dr. Marielaina Perrone discusses facial volume changes associated with major weight loss and the growing conversation surrounding GLP-1 medications such as semaglutide and tirzepatide. Why can the cheeks appear flatter? Why do smile lines, under-eye hollows, or skin laxity sometimes become more noticeable? And does every change actually need to be treated? Dr. Perrone explains why natural facial rejuvenation begins by identifying what has actually changed rather than simply adding volume. She discusses the different roles of Juvéderm dermal fillers , Botox Cosmetic , and Smooth PDO Threads , why treatment timing matters during active weight loss, and why more treatment isn't necessarily better. You'll also hear why Dr. Perrone evaluates the face and smile together, considering the relationship between the cheeks, lips, teeth, chin, and jawline when planning facial aesthetics. The goal isn't to recreate your old face. It's to preserve what looks beautiful, restore balance where appropriate, and help you continue looking naturally like yourself. Hosted by Marielaina Perrone, DDS , a dentist and facial aesthetics provider in Henderson, Nevada, serving the Las Vegas Valley . Smile & Aesthetics — where dentistry, facial harmony, confidence, and personalized care come together.

