Peptide of The Week

Hosted by JD Denham and Will Haas, The Peptide of The Week Podcastis your no-BS guide to peptides, performance, and total body optimization. Whether you’re an athlete, a high performer, or just hungry to feel better, move better, and live stronger this show’s for you. JD and Will dive deep into real-world protocols, hard-earned lessons, and the science behind what actually works. With expert guests and raw conversations, you’ll get everything from cutting-edge peptide talk to diet, training, recovery, and mindset. No fluff. No filters. Just the tools to rebuild your body and upgrade your life.

Peptide of The Week is a health podcast hosted by JD Denham and Will Haas, with 121 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

JD Denham and Will Haas hosts Peptide of The Week, a health show with 121 episodes published.

Our AI reads these to draft pitches. Use them as grounding for a pitch that cites a real guest and a specific topic.

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  Episode #123

  Peptide Q&A #55 – Peptide Sensitivity, COA Verification, Cortisol & Sleep & Insulin Resistance

  Aug 20, 20261h 19mS1

  Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas are joined by peptide consultant Michael Vandal for a deep dive into peptide sensitivity reactions, how to spot a fake Janoshik COA, fixing cortisol and sleep, insulin resistance on secretagogues, and how to bulk while staying on R. Chapters: 00:00 – Intro & How Michael Joined the Team 03:36 – Warrior Maker Coaching Program Launch 07:49 – More Than Fitness: Business & Community 08:28 – Personal Life Updates 10:28 – Q&A Begins 11:14 – Q&A: Peptide Hypersensitivity & Histamine Reactions 18:30 – Q&A: Adding Tessa to a Hyrox Athlete's Stack 23:13 – Q&A: How to Verify a Janoshik COA 26:10 – Q&A: High Estrogen & R Plateau (Age 57) 38:19 – Q&A: Cortisol, Water Retention & Sleep Fixes 48:12 – Q&A: Muscle Maintenance After Cancer Surgery 55:01 – Q&A: Do Collagen Peptides Actually Work? 58:52 – Q&A: Insulin Resistance & GLP Stacking 1:05:45 – Q&A: R Dosing for Bulking 1:13:06 – Q&A: Losing the Last 15 Pounds 1:17:10 – Outro & Coaching Program Reminder We cover: • Severe Peptide Sensitivity to CJC and Wolverine: Why blended peptides use a binding ingredient that some people are genuinely allergic to, why single peptides are the right next step, and why sourcing should be questioned first • How to Verify a Janoshik COA and Spot Fakes: Why the unique code at the bottom is everything, how to verify it on Janoshik's site, and why photoshopped COAs always crop out that code • 44-Year-Old HYROX Athlete — Add Tesamorelin or Go Straight to HGH: Why HGH wins at 44, why SLU-PP-332 helps endurance and nutrient partitioning, and why bumping Wolverine to at least 1 mig daily matters for athletes • High Estrogen on TRT with No Symptoms: Why 1067 total T explains the elevated estrogen, why the three symptoms to watch for are the real indicator, and why an AI is not needed without symptoms • Cortisol, Water Retention and Wrecked Sleep — Non-DSIP Solutions: The glycine, ashwagandha, magnesium glycinate and slow-release melatonin protocol that fixed JD's sleep, why Selank beats Semax for cortisol, and why Epithalon helps reset circadian rhythm • Collagen Peptides — Do They Actually Work: Why powdered collagen supplements produce modest results at best and why BPC, TB-500 and GHK-CU are the real collagen peptides worth taking • 53-Year-Old Female Post-Gastrectomy and Mastectomy: Why HGH and secretagogues are off the table, why SS-31 plus MOTS-C are the right longevity tools, and why creatine is non-negotiable for muscle preservation • Insulin Resistance on Secretagogues: Why growth hormone peptides blunt insulin sensitivity over time, why pulling the secretagogue is the first move, and why an endocrinologist should be in the picture • Bulking While on R: Why dropping to 1.5 migs every five days keeps food noise at bay while allowing enough appetite to eat for muscle, and why protein per pound of body weight is the only number that matters • 27-Year-Old Down 80 Pounds — Last 15 to Lose: Why adding muscle is the only way to raise metabolism enough to drop the final pounds and why SLU-PP-332, 5-Amino-1-MQ and MOTS-C hit fat from three different angles Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results. You're a warrior. Act like one. Join The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

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  Episode #122

  Peptide of the Week: Blood Work, Gut Health & Gear – With Dr. Scott Collie

  Aug 17, 20261h 9mS1

  Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with their personal functional medicine doctor and longtime friend, Dr. Scott Collie, for a deep dive into blood work, cardiovascular health, gut health, thyroid, and what actually matters when you are running gear or peptides. Chapters: 00:00 – Intro: Dr. Scott & Talking Real Food (Italy Recap) 05:29 – The Truth About "Running Gear" 06:15 – TRT vs. Steroid Cycles Explained 10:22 – Why Bloodwork Timing Matters On vs. Off Cycle 12:58 – Blood Sugar, Insulin & GLP-1s 17:45 – Kidney, Liver & Iron Health Markers 22:25 – Understanding Cholesterol: LDL, HDL & VLDL 27:31 – Thyroid Health & Hashimoto's 30:06 – Homocysteine & Methylation 35:13 – Rapid Weight Loss & Gallbladder Risks 39:16 – Inflammatory Markers & Heart Damage Warning Signs 46:02 – Top Supplements & Peptides for Cycle Support 53:41 – Cycle Timing & When to Test Blood 1:01:51 – Hydration & Final Thoughts 1:06:07 – Outro & Where to Find Dr. Scott We cover: What functional medicine actually looks at – Standard doctor panels are a snapshot, not a full picture – Dr. Scott runs up to 75 markers including cardiovascular, inflammatory, kidney, thyroid, and gut markers – Most insurance doctors stop at LDL and HDL, missing the full story completely – You need particle size, not just cholesterol weight, to understand your true cardiovascular risk Cardiovascular markers that matter – APOB: umbrella marker for all arteriosclerotic particles including VLDL, LDL, and IDL – Particle size is critical: anabolic steroids shift particles to small dense LDL, the type that sticks and clogs arteries – Myeloperoxidase and LP-PLA2: direct markers of vascular inflammation most doctors never run – Triglycerides plus elevated liver enzymes (AST/ALT) almost always means fatty liver, no ultrasound needed – Fibrinogen: a clotting protein made by the liver, high fibrinogen plus high insulin plus high triglycerides is a walking time bomb, especially for steroid users – CRP (C-Reactive Protein): one of the best inflammatory markers available, if it is high something serious is going on Homocysteine, the underrated killer – Homocysteine scars the inside of your arteries so plaque particles can park and stick – Now being studied as an Alzheimer's marker as well – Dr. Scott wants it at 7 or below, many people are at 9 to 50 – Fix: methylate with B6, B12, and methyl folate, simple and cheap – TRT alone will elevate homocysteine, so methylating is a must for anyone on testosterone ⚖️Retatrutide and rapid fat loss, what to watch – Losing fat very fast can back up bile flow and cause gallstones, not kidney stones – Check alkaline phosphatase and GGT before starting Reta if there is any gallbladder history – Signs of gallbladder issues: bloating, belching, pain under right rib cage, high-fat meal distress, floating stools – Floating poop is not a good sign, it means fat is not being absorbed properly – Blood sugar, triglycerides, and inflammatory markers improve dramatically and quickly on Reta Blood work timing for gear users – Best time to test: before the cycle starts, to establish your baseline – After the cycle ends: retest to confirm you returned to baseline – Mid-cycle testing will look alarming by design, be ready for that – If you do not know what different esters are, you are not ready to run gear Follow Dr. Scott Collie: Website: https://heydrscott.com/ Facebook: https://www.facebook.com/DrScottCollie/ Instagram: https://www.instagram.com/hey_dr_scott/ Join The Community: https://www.skool.com/peptideoftheweekcommunity Follow us: Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

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  Episode #121

  Peptide Q&A #54 – Peptide Blends Achilles Surgery Recovery, Adderall Detox & HGH vs IGF-1

  Aug 13, 20261h 1mS1

  Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover Achilles tendon surgery recovery, why CJC histamine reactions are increasing, getting off Adderall at 18, switching from Tirzepatide to Retatrutide, running HGH with IGF-1 LR3, and whether peptide blends really mix evenly.Chapters:00:00 – Intro & Warrior Makers Coaching Launch03:56 – Building Better Men & YouTube Ban Update06:15 – Where to Find the Podcast (Spotify, Rumble & More)07:27 – Upcoming Guest: Water & Hydration08:57 – School Platform & Free Resources09:51 – Q&A: Peptides for Achilles Surgery Recovery (Age 68)13:51 – Q&A: Switching CJC/SS31 for Muscle Gain (Age 41 Female)21:16 – Q&A: Getting Off Adderall Safely (Age 18)27:34 – Q&A: Transitioning from Tirzepatide to Retatrutide33:27 – Q&A: Do Wolverine Blend Ratios Mix Evenly?37:21 – Q&A: Running IGF-1 LR3 with HGH40:17 – Q&A: Best Stack When Cycling Off Retatrutide44:17 – Q&A: Low Sex Drive, LH & HCG Protocol (Age 44)52:28 – Q&A: Cutting Body Fat Before Vacation (Age 33)56:19 – Q&A: HGH vs IGF-1 for Lean Muscle (Age 42 Female)59:44 – Outro & Coaching Call ReminderWe cover:• Achilles Surgery Recovery for a 68-Year-Old: Why starting Wolverine three weeks before surgery matters, why hyperbaric chambers expedite healing, and how to keep her moving without overdoing it• CJC Histamine Reactions Are Increasing: Why JD is hearing more and more bad reactions and why switching to Tesamorelin is the smarter, safer move for women• Tesamorelin Dosing for Women: Why 500 micrograms is the right starting point, why bumping in 250 mcg increments prevents water retention, and why AOD stacked with Tessa transforms women's bodies• 18-Year-Old Getting Off Adderall: Why C-Max, Tesofensine and Dihexa are the peptide answer and why getting off drugs isn't pain-free no matter what you take• Tirzepatide to Retatrutide Transition for a HYROX Athlete: Why pulling the band-aid and starting at 3 migs works, why SLU-PP-332 helps with nutrient partitioning and endurance, and why Thymosin Alpha-1 handles inflammation• Do Peptide Blends Mix Evenly in the Syringe?: Why aqueous solutions mix uniformly unlike oil and water and why this concern is probably overthinking it• HGH vs IGF-1 LR3 Can You Run Both?: Why JD runs them together regularly, why there's no definitive proof it's dangerous, and why HGH alone already blows away any secretagogue• Should You Take Breaks from Retatrutide?: Why tolerance builds over time, why Tesofensine is a good weaning tool, and why building your base means you shouldn't need it forever• Police Officer at 21% Body Fat Getting Ripped: Why HCG should run alongside TRT, why MK-677 may be a better choice than HGH right now, and why fasting is the most underrated tool for men over 40• 42-Year-Old Female with No IGF-1 Response to Secretagogues: Why timing before blood draw skews results, why 1 IU of HGH is the cleanest answer, and why AOD plus Tesamorelin is the best women's fat-burning duoYou're a warrior. Act like one. Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Join The Community: https://www.skool.com/peptideresearchinstitute/aboutSubscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

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  Episode #120

  Peptide of the Week: TRT, Peptides & Longevity With Jay Campbell

  Aug 10, 20261h 57mS1

  Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down live for the first time in studio with Jay Campbell, the godfather of TRT, bestselling author, and one of the most respected voices in peptides and optimization. This one goes deep. Chapters: 00:00 – Intro 00:09 – Welcoming Jay Campbell 03:53 – How JD Met Jay Campbell 05:24 – Jay's Inner Work & Letting Go of Ego 13:47 – Books That Shaped Jay's Mindset 19:14 – From Corporate Wage Slave to Entrepreneur 28:18 – Growth Through Adversity & Marriage 32:55 – Masculine/Feminine Dynamics 39:53 – Being Present as a Father 45:51 – State of the Peptide Industry & Fake Products 48:28 – Regulation, FDA & the Future of RUO 57:30 – Why Doctors Resist Peptides & How to Source Safely 1:15:02 – New Peptide Innovations: Clotho, Lepto & More 1:23:48 – Jay's Personal Stack & Key Supplements 1:39:18 – Foundations First: Diet, Discipline & Fasting 1:55:32 – Book Plug & Outro We cover: The upper game board of life – Jay's been doing ego deconstruction work with a spiritual coach since November, 9 months in – Two game boards: the lower (money, success, achievement) and the upper (becoming an ethical human being) – Most driven men are unknowingly chasing their father's validation, identifying that changes everything – Sobriety and internal work are the foundation of real growth, JD and Will share their parallel journey The peptide industry, what's coming – 95% of people speaking about peptides have no idea what they're talking about – American Peptide Association working toward a single-source triple validation certification, expected by end of 2027 or early 2028 – CGMP, green-lit Chinese facilities only, avoid telegram list sourcing at all costs – Fake Retatrutide being sold for $59.99, if you're buying it that cheap, you know it's fake – The integrity of the owner is the only real difference between a research use company and a 503A pharmacy ⚗️ SS-31 vs MoTC, the new intel – Don't stack SS-31 and MoTC together, run them in separate month-long cycles – If stacking: MoTC during the week, SS-31 on weekends – High dose SS-31: a trusted source is doing 15 to 30mg daily for one month, describing it as the greatest physique transformation of his life – SS-31 massively upregulates cardiolipin, jacks mitochondrial oxidative capacity, veins pop, dramatic leanness Metformin, the underrated longevity tool – 250mg XR AM and PM, increases Akkermansia in the microbiome – Akkermansia is the last line of gut defense, kills SIBO, Candida, and makes you virtually impervious to respiratory illness – Also improves insulin sensitivity, glucose control, and HDL – Stop a week before a power meet, transiently lowers IGF-1 max output BAM (BioBam), the strongest thermogenic Jay has ever used – 2 grams per day (250mg caps, 2 AM and 2 PM to start, build to 4 caps twice daily) – Burns pure fat, does not touch muscle – Run 4 to 6 week cycles, do NOT stack with MoTC, SS-31, NAD+, or SLUPP – Stack with Bio-Recharge (C60, pomegranate, Urolithin A) to protect mitochondria This isn't theory, this is real-world experience working with hundreds of people and seeing what actually works. Subscribe for more no-fluff peptide education every week. Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/ Follow Jay Campbell: Website: https://jaycampbell.com/free-info/ Instagram: https://www.instagram.com/jaycampbell1971/ Join The Community: https://www.skool.com/peptideoftheweekcommunity

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  Episode #119

  Peptide Q&A #53 – TRT for Low T, Pituitary Tumor Cautions & Peptide Timing on Retatrutide

  Aug 6, 20261h 3mS1

  Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! Will's back from Italy engaged! In this week's Peptide Q&A, JD Denham and William T. Haas cover what peptides to stop before blood work, how to sequence a cellular rebuild stack, Tesamorelin timing on Retatrutide, TRT for a truck driver with total T of 396, and why a pituitary tumor changes everything. Chapters: 00:00 – Intro & Welcome Back 00:40 – The Proposal Story 07:00 – Upcoming Weekend Retreat Announcement 09:00 – Big Guests Coming to the Podcast 11:39 – Q&A: Peptides to Stop Before Blood Work 13:28 – Q&A: Cellular Rebuild Stack & Sequencing 23:22 – Q&A: Sermorelin & Ipamorelin Dosing 29:49 – Q&A: BPC-157 Sublingual vs Oral 32:26 – Q&A: Reconstituted Reta Shelf Life 36:36 – Q&A: TRT Protocol for Low Testosterone 43:14 – Q&A: Timing Tesa/Ipa with Reta 48:25 – Q&A: Combining Multiple Peptides in One Injection 49:20 – Q&A: HGH vs CJC/Ipa Timing with GLP-1 50:36 – Q&A: Muscle Growth Peptides with Pituitary History 53:19 – Prague Trip Recap 59:54 – Outro & Feedback Request We cover: • What to Stop Before Blood Work: Why secretagogues, MK-677, HCG, Kisspeptin and biotin can all skew your labs and how long to stop each before testing • Cellular Rebuild Stack all at Once or Sequenced?: Why Fox04 first clears the trash, why SS-31 must come before MOTS-C, and why throwing the kitchen sink in at once defeats the purpose • Epithalon Dosing Explained: Why 100 migs twice a year is the standard, why 10 migs for 10 days and 5 migs for 20 days are both correct, and why Paul Bakhtiar starts everyone here • Sermorelin + Ipamorelin at 260 Down to 238 should You Up the Dose?: Why a caloric deficit blunts IGF-1 response, why winning streaks aren't the time to add more, and how to use plateau busters instead • BPC-157 Sublingual vs Oral for Gut Health: Why BPC was born in gastric juices and why oral capsules beat sublingual for gut-specific use every time • How Long Can You Keep a Reconstituted Retatrutide Vial: Why 28 days is the bacteriostatic water standard not a cliff edge and why buying the right vial size solves the problem • TRT Protocol for a Truck Driver with Total T of 396: Why high body fat raises estrogen and SHBG, why 180-200 migs of test twice weekly is the starting point, and why life changes in three weeks • Tesamorelin + Ipamorelin Timing When on Retatrutide: Why morning fasted dosing beats nighttime circadian alignment when GLP-1 is slowing gastric emptying and why the two peptides should never be split up • HGH vs CJC for Muscle Growth Over 50: Why actual HGH wins every time and why splitting the dose morning and night is worth exploring • Benign Pituitary Tumor What Peptides Are Safe: Why HGH and secretagogues are off the table, why creatine and protein are the real answer, and why IGF-1 LR3 still carries risk Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results. You're a warrior. Act like one. Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Join The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

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