Talk BIO to Me

What happens when you mix a disco-dancin' podcaster with some of the brightest minds in biotech? You get Talk BIO to Me. Recorded live at SynBioBeta, this interview series takes you inside the world of synthetic biology through conversations with pioneering scientists, founders, investors, and AI innovators building the future of life.

Talk BIO to Me is a business podcast hosted by Unknown Host, with 9 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

Unknown Host hosts Talk BIO to Me, a business show with 9 episodes published.

Our AI reads these to draft pitches. Use them as grounding for a pitch that cites a real guest and a specific topic.

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  Episode #8

  So You Want to Design a Genome - with Samuel King, Stanford

  Aug 4, 202617 min

  What happens when you train an AI model not on the internet, but on millions of genomes? Samuel King, a PhD candidate at Stanford, working at the intersection of AI and bioengineering, joins host Flo Lumsden to unpack it — including how his team used AI to generate the first fully functional bacteriophage genome from scratch, and why that could mean far more targeted treatments for antibiotic-resistant infections. They also get into the designer baby question and what makes a PhD less narrow than people assume. Recorded live at SynBioBeta 2026, where the scientists, the machine learning crowd, and (increasingly) the compute giants all show up to compare notes. About Samuel King: Samuel King is a Ph.D. candidate in Bioengineering at Stanford University and the Arc Institute. His current research aims to advance human and planet health by leveraging large language models trained on DNA for biological discovery and design. He previously co-founded a genomics biotech start-up and received an M.S. from Stanford and B.Sc. from the University of British Columbia. Connect with Samuel: Website Linkedin

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  Episode #7

  The Wright Brothers Moment of Biology: Genyro Founders Adrian Woolfson & Kaihang Wang

  Jul 21, 202619 min

  This one's a joyride. Flo catches Adrian Woolfson , CEO and co-founder of Genyro , and his co-founder Kaihang Wang at SynBioBeta for a conversation that starts with genome writing and ends somewhere between Doctor Who and a custom unicorn order form. Along the way, the two break down how bringing the humble "page number" from publishing into DNA assembly made their process a million times more accurate, why that could shrink personalized cancer vaccines from months to days, and how one of their collaborators built the first-ever computer-designed new species — biology's own "Wright Brothers moment." It's big ideas — DNA as a programmable material, storing your entire photo library in a strand of genetic code, redesigning crops for a hotter planet — delivered with a ton of laughs and genuine, can't-help-it enthusiasm. But it's not all fun and games: Adrian and Kaihang are clear-eyed about the responsibility that comes with this power, making the case that this technology must be used safely and ethically, with real reverence for preserving the nature we're learning to rewrite. Come for the science, stay for the unicorn with wings. Talk BIO to me!

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  Episode #6

  Inside Cradle: How AI Is Accelerating Scientific Discovery with Elise de Reus

  Jul 15, 202613 min

  Ever wonder what happens when a wet lab biologist and a bunch of Google machine learning engineers decide to start a company? You get Cradle — and on this episode, co-founder Elise de Reus joins host Flo Lumsden to explain why. Elise breaks down how Cradle turns protein design into a genuine back-and-forth between scientists and machine learning models — less "here's your AI, unbox it and go," more "let's figure this out together." Flo presses her on what "ML-native" actually means (spoiler: it involves a scissors analogy that somehow works), and Elise explains why the real magic isn't the model alone — it's the loop itself. They also get into the bigger picture: antibodies that skip the mouse, enzymes that survive your laundry machine, and why designing proteins faster — and in the loop, not in isolation — could mean faster answers for the diseases we're all still waiting on treatments for. Recorded live at SynBioBeta , where the scientists, the machine learning crowd, and (increasingly) the compute giants all show up to compare notes. White Paper: https://www.cradle.bio/whitepaper

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  Episode #5

  AI Is About to Redesign Life Itself: SynBioBeta's John Cumbers Explains

  Jul 7, 202614 min

  Join host Flo Lumsden as she sits down with John Cumbers , CEO and founder of SynBioBeta , at the world's largest synthetic biology conference this past May. In this conversation, John shares how AI is fundamentally reshaping the field of biology — from large language models designing novel enzymes and antibodies to full-stack scientific innovation. Discover the most exciting breakthroughs happening right now, including xenotransplantation with humanized pig organs, consumer biotech products like probiotic hangover cures, and genetically engineered glowing plants. John also reveals what he's most excited about at the intersection of AI and biotech, the challenges that lie ahead, and why he believes we're approaching AGI (Artificial General Intelligence). Plus, learn the origin story of SynBioBeta — how a small meeting of 150 people in a law firm grew into a 2,000+ person conference with over 100 exhibitors and sponsors — and why creating community and "paying it forward" is at the heart of everything he does. Outline with Timecodes: 00:00 - Introduction & Podcast Overview 00:36 - SynBioBeta Origin Story 02:17 - John Cumbers, CEO & Founder Introduction 02:23 - Evolution of SynBioBeta: From 150 to 2,000+ Attendees 02:57 - John's Passion for Event Production & Community Building 03:42 - "Paying It Forward" Culture & Success Stories 04:31 - Science as a Competitive Advantage for Startups 05:18 - AI at the Intersection of Biotech 05:30 - Large Language Models for Genes and Genomes 06:22 - How AI is Designing Novel Enzymes & Organisms 07:03 - Antibody Development for Drug Discovery 07:14 - Challenges & Limitations of AI Implementation 08:09 - Healthcare Innovations: Xenotransplantation 08:55 - Consumer Biotech Applications 09:03 - Zbiotics & Probiotic Products 09:18 - GLP-1 Peptides & Cellular Reprogramming 10:17 - New Innovations: Glowing Plants & Hardware/Software Tools 11:04 - Full-Stack AI Integration in Biotech 12:12 - SynBioBeta 2026 Themes & Community Sessions 13:00 - Closing Remarks

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  Episode #4

  Can AI Debug Biology? Nicholas Larus-Stone, AI @ Benchling

  Jun 29, 202610 min

  For years, AI has helped scientists organize data and streamline research, but it's now beginning to tackle biology's toughest scientific challenges. In this episode, Flo sits down with Nicholas, Head of AI at Benchling, to discuss why the physical world has been AI's biggest blind spot—and why that's finally changing. From generative protein design to the future of drug discovery and diagnostics, Nicholas explains how biology is increasingly being engineered in silico (by compute) before it reaches the lab. Plus, he shares what excites him most about the next wave of AI-powered biology - the future of the bioeconomy! Connect: Nicholas on Linkedin: https://www.linkedin.com/in/nlarusstone/ Benchling: https://www.benchling.com/

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