Research Translation Podcast
Alzheimer’s and Amyloid 2: Mistakes Of Mice and Men
Jun 3, 202623 minS0
<p>Last week we reviewed two seminal studies from the 1990s, both showing mathematically that amyloid plaques are, at best, an inconsistent bystander in Alzheimer’s Disease. Plainly, they are not the driving cause.</p><p>Hardcore believers may have ignored or rationalized the findings from these small but pivotal autopsy studies. A decade later however, there would be no refuge and no rescue when two trials shook the neurology community, forcing even the most avid and invested supporters to abandon ship.</p><p>Of Mice</p><p>To test dementia treatments, researchers needed test subjects. In the early ‘90s gene...
