The Immunology Podcast

A podcast featuring conversations with immunologists from around the globe. Brought to by STEMCELL Technologies.

The Immunology Podcast is a science podcast hosted by Unknown Host, with 176 episodes on record and a Required Pod Score of 80.

Unknown Host hosts The Immunology Podcast, a science show with 176 episodes published.

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  The Immunology Podcast

  Ep. 141: “Unlocking T Cell Immunity” Featuring Dr. Roger Geiger

  Sep 22, 20261h 13m

  Guest: Dr. Roger Geiger is a Group Leader at the Institute for Research in Biomedicine in Bellinzona, Switzerland, and leads a research group at the Technical University of Dresden in Germany. He discusses how his lab studies the metabolic regulation of T cell function and explores engineering bacteria to deliver therapeutic payloads directly to tumors. He also explains how arginine metabolism can enhance anti-tumor T cell responses and how naïve T cells remain metabolically prepared to rapidly respond to immune challenges. Featured Products and Resources: Stay up-to-date with the latest in cell therapy news. Download a free wallchart on the production of CAR T cells. The Immunology Science Round Up C. difficile Shapes Gut Development – Early-life C. difficile exposure alters intestinal stem cell behavior and leaves lasting changes in gut development. The Serotonin–Asthma Connection – ILC2-derived serotonin amplifies airway inflammation and activates sensory neurons to promote asthma and cough hypersensitivity. IgA Fuels Liver Inflammation – IgA binding to liver myeloid cells is associated with IL-1-linked inflammation and liver injury in alcohol-associated liver disease. Serotonin Drives Severe COVID-19 – Platelet-derived serotonin promotes blood clotting and lung dysfunction during SARS-CoV-2 infection, helping explain greater disease severity with age. Image courtesy of Dr. Roger Geiger Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

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  The Immunology Podcast

  Ep. 140: “T Cells Under Pressure” Featuring Dr. Martin Prlic

  Sep 8, 20261h 12m

  Guest: Dr. Martin Prlic is a Professor in the Vaccine and Infectious Disease Division at Fred Hutch Cancer Center. He discusses the challenges of studying human immunology and how his lab uses advanced single-cell technologies to understand T cell responses across healthy, inflamed, and tumor tissues. He also explores the biology of tissue-resident T cells, how inflammation shapes their function, and immune cell interactions at the maternal-fetal interface. Featured Products and Resources: Decorate your lab with a Nature Protocols wallchart outlining the production of therapeutic CAR T cells. Find high-quality antibodies and integrate them into your workflow! The Immunology Science Round Up lncRNA Regulates Gut Immunity – An IBD-associated long noncoding RNA promotes immune tolerance by enhancing regulatory T cell function and limiting inflammatory T cell responses. Trust in Research Antibodies – An investigation identified nearly 19,000 apparently manipulated antibody validation images across products sold by 15 research antibody vendors. Targeting Melanoma with mRNA – A Phase III trial found that a personalized mRNA neoantigen therapy combined with KEYTRUDA improved recurrence-free and distant metastasis-free survival compared with KEYTRUDA alone after melanoma surgery. Beyond Shingles Prevention – A recombinant shingles vaccine was associated with a lower long-term risk of several cardiovascular outcomes, supporting further studies of its potential cardioprotective effects. Engineering Myeloid Immunotherapy – Expandable granulocyte-monocyte progenitors provide a scalable platform for engineering macrophages that can target blood and solid tumors. CAR T Cells Meet Glioblastoma – Responses to CAR T cell therapy for glioblastoma are associated with the surrounding immune environment, with NK cells linked to response and regulatory T cells and suppressive myeloid cells linked to resistance. Image courtesy of Dr. Martin Prlic Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

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  The Immunology Podcast

  Ep. 139: “Advances in Myeloid Cell Immunology” Featuring Dr. Miriam Merad

  Aug 25, 20261h 34m

  Guest: Dr. Miriam Merad is Director of the Precision Immunology Institute and a Professor at the Icahn School of Medicine at Mount Sinai. She discusses how myeloid progenitors and macrophages shape the tumor microenvironment, and how dendritic cells support tertiary lymphoid structures and anti-tumor immunity. She also explores the role of chronic inflammation in aging and disease, and shares her perspective on the importance of biomedical research in protecting human health. Featured Products and Resources: Get a free wallchart of the frequencies of human cell types in blood-related sources. Subscribe to Human Immunology News to keep up with the latest news, research, policy, and jobs in the community. The Immunology Science Round Up Viral Reactivation in COVID-19 – Chronic viruses frequently reactivate during severe COVID-19, with distinct patterns associated with inflammation, disease severity, recovery, and long COVID. Safer Antibodies During Pregnancy – Fusing therapeutic antibodies to albumin reduces their transfer across the placenta while preserving prolonged circulation, offering a strategy to limit fetal drug exposure during pregnancy. Self-Sustaining Regulatory T Cells – Engineering regulatory T cells with a self-sustaining IL-2 signaling system improves their persistence and ability to prevent autoimmune diabetes in mice. Where Tuberculosis Persists – Mycobacterium tuberculosis persists in lymph nodes by forming infected monocyte-derived niches that evade recognition by Mtb-specific T cells despite activating antimicrobial responses. Image courtesy of Dr. Miriam Merad. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

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  The Immunology Podcast

  Ep. 138: “Reprogramming Autoimmunity” Featuring Dr. Pere Santamaria

  Aug 11, 20261h 20m

  Guest: Dr. Pere Santamaria is a Professor at the Cumming School of Medicine at the University of Calgary and Group Leader at the Barcelona Institute. He discusses how his lab studies the mechanisms underlying autoimmune diseases, with a focus on regulatory T cell biology and antigen-specific immune tolerance. He also explains how his team developed a nanomedicine platform that reprograms autoreactive T cells into regulatory cells, offering a targeted approach to treating autoimmune disorders without suppressing normal immune function, and shares the challenges of translating this technology from the lab to the clinic. Featured Products and Resources: Find the right antibodies for your research and start integrating them into your workflow. Get a free copy of a Nature Protocols wallchart outlining the production of therapeutic CAR T cells. The Immunology Science Round Up Maternal Vaccine Against GBS – A Phase I/II trial shows that a maternal hexavalent Group B Streptococcus vaccine is safe and elicits robust antibody responses in both mothers and infants. Decoding Treg Differentiation – TCR specificity and antigen presentation context determine regulatory T cell differentiation and phenotype, providing a framework for antigen-specific immune tolerance. A Microbiota–Autoimmunity Axis – Disrupted dendritic cell development promotes gut dysbiosis that drives inflammatory dendritic cell expansion and systemic autoimmunity. Programming Regulatory T Cells – TCR specificity and antigen presentation context determine regulatory T cell differentiation and phenotype, providing a framework for antigen-specific immune tolerance. Image courtesy of Dr. Pere Santamaria. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

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  The Immunology Podcast

  Ep. 137: “Tissue Specificity of miRNAs” Featuring Dr. Brian Brown

  Jul 28, 20261h 14m

  Guest: Dr. Brian Brown is a Professor at the Icahn School of Medicine at Mount Sinai. He discusses how his lab develops innovative technologies to study the immune system and advance new therapeutics, from T cell engineering to mRNA-based medicines. He also explores how microRNA-guided targeting can improve the precision of mRNA therapeutics, how different tissues shape immune responses, and the importance of effective science communication. Featured Products and Resources: Learn more about STEMCELL’s optimized protocols and reagents for immunotherapy research. Download this free conference toolkit to make the most out of your experience this conference season. The Immunology Science Round Up Sindbis in Cerebrospinal Fluid – Scientists have found evidence that Sindbis virus can invade the human central nervous system and cause neurological disease. A Skin–Lung Reflex – Activation of sensory neurons in the skin suppresses allergic airway inflammation through a vagus nerve–mediated neuroimmune reflex. Microbiome Enhances Cancer Immunity – Gut bacteria promote anti-tumor immunity by converting tryptophan into indoles that enhance immune responses and inhibit melanoma growth. Macrophages Drive Healthy Aging – Restoring macrophage clearance of senescent neutrophils reverses age-related decline across multiple organs in mice by blocking EP2 signaling. Image courtesy of Dr. Brian Brown Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

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