The ImmunoVerse™

The ImmunoVerse™ is a monthly podcast exploring the past, present and future of immunotherapy and delving into every intricacy of the body's immune system. Hosted by Moffitt Cancer Center President and CEO, Dr. Patrick Hwu , each episode highlights the trailblazing visionaries who are pushing boundaries in this ever-evolving, world-changing field.

The ImmunoVerse™ is a health podcast hosted by Moffitt Cancer Center, with 18 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

Moffitt Cancer Center hosts The ImmunoVerse™, a health show with 18 episodes published.

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  The ImmunoVerse™

  Reprogramming Macrophages: From Tissue Repair to Cancer Immunotherapy, ft. Dr. Miriam Merad

  Jun 25, 202622 min

  Dr. Patrick Hwu speaks with Dr. Miriam Merad, a leading physician-scientist in dendritic cell and macrophage biology at the Icahn School of Medicine at Mount Sinai. Dr. Merad reflects on her path from medicine to immunology and discusses how tissue-resident macrophages help maintain organ health but can also be fooled by tumors into supporting cancer growth. The conversation explores ways to reprogram macrophages for cancer treatment, the link between aging, inflammation and cancer risk, and the importance of multidisciplinary collaboration, data science and sustained research investment in advancing future cures. What You’ll Learn with Dr. Miriam Merad The role of macrophages in cancer, inflammation and tissue repair Why cancer can exploit the body's natural wound-healing processes New immunotherapy approaches that target and reprogram macrophages The connection between aging, chronic inflammation and cancer risk The future of macrophage-based cancer treatments Mentorship strategies for developing the next generation of immunology leaders

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  The ImmunoVerse™

  Inside the Microbiome: Fiber, Gut Health and Immunotherapy, ft. Dr. Jennifer Wargo

  May 21, 202625 minS0

  <p>Dr. Patrick Hwu sits down with Dr. Jennifer Wargo, Professor of Surgical Oncology and Genomic Medicine, leader of the platform for innovative microbiome and translational research at The University of Texas MD Anderson Cancer Center, to discuss how the tumor microbiome and host factors shape cancer development and response to immunotherapy.</p> <p>Together, they explore the growing evidence that cancer is influenced not only by tumor genetics and the immune system but also by the communities of bacteria that live within and around tumors. Dr. Wargo explains how differences in the gut and tumor microbiome can affect immune...

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  The ImmunoVerse™

  Reprogramming Metabolism to Power Immunotherapy, ft. Dr. Greg Delgoffe

  Apr 22, 202624 minS0

  <p>Dr. Patrick Hwu sits down with Dr. Greg Delgoffe, professor of immunology at the University of Pittsburgh and director of the Tumor Microenvironment Center at UPMC Hillman Cancer Center, to explore how the tumor microenvironment functions as a complex, dynamic ecosystem that shapes the success or failure of cancer immunotherapy.</p> <p>Together, they unpack how tumors are far more than just cancer cells—consisting instead of diverse populations of immune cells, stromal cells, and cancer cells all interacting within a shared and often hostile environment. Dr. Delgoffe explains how cancer cells actively reshape that environment by competing for an...

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  The ImmunoVerse™

  Uncovering the Dark Matter of Cancer, ft. Dr. Bernie Fox

  Mar 25, 202624 minS0

  <p>Dr. Patrick Hwu sits down with Dr. Bernie Fox, a pioneering immunologist and chief of the Laboratory of Molecular and Tumor Immunology at Providence Cancer Institute. The conversation spans the early days of immunotherapy, including their shared training roots in the NIH Surgery Branch under Dr. Steve Rosenberg, and moves into today’s cutting-edge science.</p> <p>Dr. Fox explains the emerging concept of “dark matter” in cancer biology — the once-dismissed non-coding regions of DNA that may play a pivotal role in tumor progression and immune targeting. He discusses how these regions are now known to produce short-lived proteins that may...

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  The ImmunoVerse™

  Pioneering the Evolution of Immunotherapy, ft. Dr. Jedd Wolchok

  Feb 25, 202626 minS0

  <p>Dr. Patrick Hwu is joined by Dr. Jedd Wolchok, director of the Sandra and Edward Meyer Cancer Center at Weill Cornell, and a global leader in immune checkpoint blockade therapy. Dr. Wolchok recounts his early days in the lab of immunotherapy legend Dr. Lloyd Old and reflects on the transformational impact of CTLA-4 and PD-1 inhibitors. A key architect of these therapies’ clinical success, he shares the stories behind the trials that reshaped treatment for melanoma and beyond. The discussion also dives into the future: tackling resistance, optimizing combinations, and staying grounded in patient-focused, translational science.</p>

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