The Longevity & Lifestyle Podcast

Claudia von Boeselager is here to empower you to live at your best and reach your highest potential by sharing groundbreaking strategies, tools, and practices for your longevity and lifestyle from the world’s pioneering experts. For more, visit: LLinsider.com Welcome to The Longevity & Lifestyle Podcast! Claudia is on a mission to help 1 billion people optimize their lives and reach their fullest potential so that they can make a positive impact in the world! Tune in to learn how to increase your healthspan, improve the quality of your life and lifestyle also around entrepreneurship, managing personal finances and investing, and much more. Topics include how to optimize your health in areas such as sleep, nutrition, cognition, metabolic health, reversing diabetes, intermittent fasting, biomarkers, gut health, hormones, the female biorhythm, skin, hair, biohacking tips, supplements, mastering your mindset, improve your relationships and overall happiness, meditation, how to perform b

The Longevity & Lifestyle Podcast is a education podcast hosted by Claudia von Boeselager, with 260 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

Claudia von Boeselager hosts The Longevity & Lifestyle Podcast, a education show with 260 episodes published.

Our AI reads these to draft pitches. Use them as grounding for a pitch that cites a real guest and a specific topic.

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  Episode #260

  #260 Tommaso Barba — The Science of Psychedelics: 5-MeO-DMT, Brain Aging & Mental Health

  Jul 30, 202648 min

  What happens when the brain temporarily lets go of the identity, memories, and personal story that make you feel like “you”? In this episode of the Longevity & Lifestyle Podcast, Claudia speaks with Tommaso Barba, psychedelic researcher at Imperial College London, whose work explores consciousness, ego dissolution, 5-MeO-DMT, mental health, relationships, and the nature of the self. Tommaso explains why psychedelics are returning to mainstream science after decades of prohibition, how psilocybin, LSD, DMT, 5-MeO-DMT, MDMA, ketamine, and ibogaine differ, and why pharmaceutical companies are now investing heavily in psychedelic medicine. They examine the limitations of conventional psychiatric treatment, including the idea that depression is simply a chemical imbalance, and explore why psychedelic experiences may reach psychological, emotional, social, and spiritual dimensions that existing medications often do not address. Tommaso also shares his personal high-dose psilocybin experience, describing the dissolution of his identity, a sense of boundless awareness, and the challenge of returning to ordinary life after experiencing profound presence and connection. This conversation does not present psychedelics as casual shortcuts. It explores the importance of preparation, set and setting, skilled facilitation, integration, contraindications, and the cultural structures needed to support these powerful experiences safely. IN THIS EPISODE • Why psychedelics are entering mainstream medicine • How psychedelic research was halted for decades • Psilocybin, LSD, DMT, 5-MeO-DMT, MDMA, ketamine, and ibogaine • Why depression is more complex than a chemical imbalance • How set, setting, and integration shape outcomes • Why unsupported psychedelic use can become destabilizing • How 5-MeO-DMT is being used to study consciousness • What ego dissolution can feel like • Neuroplasticity, psychological flexibility, and mental health • Who may not be suitable for psychedelic treatment • Psychedelics, intimacy, sexuality, and relationships • The future of psychedelic medicine and psychiatry TIMESTAMPS 00:00 Introduction 02:28 Psychedelics enter the pharmaceutical mainstream 05:27 Why psychedelic research was banned 10:12 The major psychedelic compounds explained 12:46 Why modern psychiatry needs new approaches 15:34 Set, setting, and altered states 18:56 Why support and integration matter 20:23 Tommaso’s path into psychedelic research 22:41 Psychedelics, religion, and The Immortality Key 24:46 Using 5-MeO-DMT to study consciousness 26:37 What happens when the self dissolves? 27:49 Depression, neuroplasticity, and 5-MeO-DMT 30:47 Psychedelics for depression, PTSD, and addiction 32:39 Why psychedelics are not for everyone 34:02 Tommaso’s experience of ego dissolution 37:26 Presence, creativity, and intuition 39:12 Psychedelics, intimacy, and relationships 42:35 The future of psychedelic medicine 44:16 Final message: stay curious Subscribe to the Longevity & Lifestyle Podcast for evidence-informed conversations with leading scientists, physicians, researchers, and innovators shaping the future of health, longevity, and human potential. Please share this episode with someone interested in consciousness, mental health, psychedelic science, or the future of psychiatry. #TommasoBarba #Psychedelics #PsychedelicScience #Psilocybin #5MeODMT #MentalHealth #Consciousness #Neuroplasticity #EgoDeath #LongevityPodcast

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  Episode #259

  #259 Jamie Clements — How to Breathe Better: Stress Resilience, Altered States & Human Potential

  Jul 22, 202652 min

  What if the constant pressure to improve yourself is reinforcing the anxiety you are trying to escape? In this episode of the Longevity & Lifestyle Podcast, Claudia welcomes Jamie Clements, breathwork facilitator, speaker, educator, and founder of The Breath Space. Jamie shares how anxiety, depression, and panic attacks led him away from a high-performing career in finance and technology and toward a deeper exploration of breath, nervous system health, consciousness, and human potential. He explains how breathing influences the autonomic nervous system, why dysfunctional breathing can reinforce stress and anxiety, and how simple changes in breathing speed, depth, and rhythm can shift how we feel and perform. They also explore carbon dioxide tolerance, nasal breathing, breath holding, sleep apnea, altered states of consciousness, trauma-aware breathwork, and the risks of practicing deeper techniques without the right preparation or facilitator. This conversation also challenges the modern obsession with optimization. Jamie explains why high performers often find rest uncomfortable, how achievement can become tied to self-worth, and why slowing down may be one of the most powerful ways to improve creativity, energy, and performance. IN THIS EPISODE • How anxiety and panic attacks led Jamie to breathwork • Why the breath directly influences the nervous system • Signs that you may be breathing dysfunctionally • Why carbon dioxide is essential for oxygen delivery • How breath holding may build stress resilience • Nasal breathing, mouth breathing, and cognitive health • Box breathing, extended exhales, and the physiological sigh • How breathwork can create altered states of consciousness • Trauma, emotional release, and breathwork safety • Why high performers struggle to rest • The link between achievement and self-worth • Why you do not need fixing • How slowing down can improve productivity TIMESTAMPS 00:00 Introduction 03:44 Jamie’s experience with anxiety and panic attacks 06:15 Losing his job and discovering a different path 09:26 Why we underestimate the power of breathing 12:15 Ancient breathwork traditions 15:43 How breathing controls the nervous system 18:06 Using breath to change your internal state 19:33 CO2 tolerance and stress resilience 24:58 Signs you may be breathing incorrectly 27:39 The three levels of breathwork 31:13 Trauma release and breathwork safety 33:54 What an altered-state breathwork session feels like 38:29 Why high performers struggle to slow down 41:43 Purpose, ambition, and self-worth 43:24 Creating work-life harmony 48:57 The Breath Space 50:33 Why you do not need fixing ABOUT JAMIE CLEMENTS Jamie Clements is a breathwork facilitator, speaker, educator, and founder of The Breath Space. His work brings together functional breathing, neuroscience, psychology, trauma-aware practice, ancient wisdom, and nervous system regulation. Through retreats, workshops, courses, and corporate experiences, Jamie helps people move from anxiety, burnout, and disconnection toward greater awareness, resilience, and meaning. Subscribe to the Longevity & Lifestyle Podcast for evidence-informed conversations with leading experts in health, longevity, consciousness, and human performance. Please share this episode with someone who feels overwhelmed, chronically stressed, or unable to slow down. #JamieClements #Breathwork #NervousSystem #Anxiety #StressRelief #MentalHealth #Consciousness #TraumaHealing #Burnout #LongevityPodcast

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  Episode #258

  #258 Jay Campbell — Peptides, Fake Products, GLP-1 Mistakes, Quality Testing & His Top Supplements

  Jul 15, 20261h 5m

  What if the peptides and supplements you are taking contain far less than the label claims? In this episode of the Longevity & Lifestyle Podcast , Claudia welcomes back Jay Campbell , bestselling author, peptide educator, and co-founder of BioLongevity Labs and BioLongevity Supplements. Jay reveals why he believes much of the peptide and supplement market is filled with counterfeit, underdosed, or poorly tested products. He explains how consumers can investigate batch numbers, certificates of analysis, ingredient dosages, and third-party testing before trusting a product. They also explore the rapidly changing regulatory landscape around peptides and GLP-1 medications, why many people experience avoidable side effects, and why peptides should be treated as tools rather than shortcuts. Jay shares the foundations that should come first, including resistance training, adequate protein, quality sleep, metabolic health, and hormonal balance. He also reveals the three supplements he personally considers most noticeable for energy, gut health, and cognitive performance. IN THIS EPISODE • Why peptide quality and testing matter • How counterfeit and underdosed products enter the market • What batch numbers and certificates of analysis can reveal • Why proprietary blends should raise questions • The biggest mistakes people make with GLP-1 medications • Why peptides are not magic bullets • How to assess supplement labels and active dosages • When supplements should be taken fasted or with food • Jay’s top products for energy, gut health, and focus • Why education matters more than hype TIMESTAMPS 00:00 Introduction 02:26 Why Jay created BioLongevity Supplements 04:13 Peptide regulation and the changing market 11:02 Retatrutide, access, and pharmaceutical control 13:34 What peptides are and how they work 15:31 The history of peptide and bioregulator research 23:06 The future of retatrutide regulation 27:41 Fake and underdosed peptide products 29:08 How to verify peptide quality 32:27 Why many people use GLP-1s incorrectly 34:07 Creating stronger peptide testing standards 38:55 Why peptides are tools, not shortcuts 43:43 Why the supplement industry is broken 51:26 How to read a supplement label 54:01 Active ingredients and proprietary blends 58:15 How oral supplements are absorbed 59:55 Jay Campbell’s top three supplements 01:02:08 Jay’s final message JAY’S TOP THREE SUPPLEMENTS Shred Max Designed to support mitochondrial energy, exercise performance, sweating, and force production. BioGut Pro Formulated to support the gut microbiome, reduce inflammation, and address digestive imbalance. BioMind A nootropic blend designed to support calm, precise focus during demanding cognitive tasks. Explore BioLongevity Supplements and receive 20% off with code CLAUDIA20 : https://biolongevitysupplements.com/shop Subscribe to the Longevity & Lifestyle Podcast for more conversations with leading experts in longevity, health optimization, and human performance. Disclaimer: This podcast is for educational and informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before using peptides, supplements, or medications, or changing your health protocol. #JayCampbell #Peptides #Supplements #GLP1 #BioLongevity #HealthOptimization #GutHealth #BrainHealth #Mitochondria #Longevity

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  Episode #257

  #257 Dr. Dale Bredesen — Can Alzheimer's Be Prevented? New Trial Results & Brain Biomarkers

  Jul 9, 202656 min

  Ready to unlock your brain’s superpower? Download my free 5-Minute Brain Blueprint to boost mental clarity, sharpen focus, and support lifelong cognitive vitality → https://longevity-and-lifestyle.com/BRAIN What if cognitive decline is not as inevitable as we have been told? In this episode of the Longevity & Lifestyle Podcast, I welcome back Dr. Dale Bredesen, internationally recognized neurologist, bestselling author, and pioneer in the prevention and reversal of cognitive decline. Dr. Bredesen shares the findings from his latest randomized controlled trial, in which 90% of participants receiving a precision medicine protocol improved. We explore why Alzheimer’s may begin decades before symptoms appear, the biomarkers that can help identify risk earlier, and the lifestyle and medical factors that may influence cognitive health. We also discuss the role of sleep, insulin resistance, inflammation, toxins, ketones, peptides, stem cells, GLP-1 medications, psychedelics, and neuroplasticity. This conversation offers an important message: the earlier we understand what is driving cognitive decline, the greater the opportunity to act. In this episode, you’ll learn: • Why Alzheimer’s may begin decades before symptoms • What Dr. Bredesen’s latest trial revealed • The stages from prevention to dementia • Blood biomarkers linked to early decline • Insulin resistance, ketones, and brain energy • Sleep apnea and long-term brain health • Why there is no single cure TIMESTAMPS 00:00 Introduction 03:37 The Alzheimer’s trial where 90% improved 06:35 What drives cognitive decline 12:01 Why Alzheimer’s is no longer viewed as hopeless 16:08 The four stages of cognitive decline 18:22 Blood tests that may reveal risk earlier 22:22 The key drivers of Alzheimer’s 23:36 The seven foundations of brain health 25:53 Sleep targets for cognitive longevity 28:27 GLP-1s and Alzheimer’s risk 31:35 Peptides for brain health 35:59 Stem cells, exosomes, and regenerative medicine 39:32 Is there hope at every stage? 40:45 Inside the randomized clinical trial 46:18 Psychedelics and neuroplasticity 52:31 Dr. Bredesen’s final message CONNECT WITH DR. DALE BREDESEN Website: https://www.drbredesen.com Free cognitive assessment: https://www.mycqtest.com Brain biomarker testing: https://www.getabrainscan.com CONNECT WITH CLAUDIA Website: https://longevity-and-lifestyle.com Instagram: https://www.instagram.com/longevityandlifestyle LinkedIn: https://www.linkedin.com/in/claudiavonboeselager YouTube: https://www.youtube.com/@LongevityandLifestyle Subscribe to the Longevity & Lifestyle Podcast for more conversations with leading scientists, physicians, founders, and innovators shaping the future of health and human performance. #DaleBredesen #Alzheimers #BrainHealth #CognitiveDecline #DementiaPrevention #Longevity #PrecisionMedicine #Neuroplasticity #HealthyAging #LongevityPodcast

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  The Longevity & Lifestyle Podcast

  #256 Dr. Ian White — Repairing the Aging Body: Amniotic Fluid, Muse Cells & Regenerative Medicine

  Jul 1, 202659 minS256

  What if the real key to longevity is not just preventing damage - but restoring the body’s ability to repair itself? In this episode, I sit down with Dr. Ian White, a leading expert in regenerative medicine, stem cell biology, tissue regeneration, and longevity science. We explore how amniotic fluid, Muse cells, and regenerative signaling may help support healing, reduce inflammation, and change the future of longevity medicine. We also break down what regenerative medicine actually is, how it differs from the way most people talk about stem cells, what matters most for safety, and how this field could reshape the way we think about aging and recovery. In this conversation, we cover: 00:00 - The accidental discovery that changed regenerative science 00:40 - Could the answer to longevity begin before birth? 02:23 - Dr. Ian White’s path into regenerative medicine 05:13 - Why some animals regrow tissue and humans do not 07:26 - What changes in the body’s repair systems with age 09:29 - Why amniotic fluid is so scientifically interesting 12:55 - What regenerative medicine really means 15:05 - Longevity, healing, and the biology of repair 16:30 - Stem cells vs regenerative medicine 21:05 - Regulation, safety, and responsible clinical use 24:13 - Tissue repair and real-world applications 28:37 - Brain health and regenerative medicine 31:39 - Rejuvenation and the future of anti-aging medicine 39:05 - Muse cells and why they matter 43:40 - Who may benefit most from these therapies 46:37 - How to approach regenerative medicine responsibly 50:23 - Space aging research and the future of longevity science 54:25 - Final thoughts on healing, aging, and what comes next If you enjoyed this episode, subscribe and share it with someone serious about living longer, healthier, and better. #Longevity #RegenerativeMedicine #StemCells #HealthyAging #Biohacking #TissueRepair #AntiAging #HealthOptimization

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