The Science of Skin

The Science of Skin is a podcast for those who want to be in-the-know about what's trending in topical skincare and learn about new therapies that are shaping the future of dermatologic care. Hosts Dr. Patti Farris and Dr. Ted Lain are board certified dermatologist, recognized experts in topical skincare and co-founders of the Science of Skin Summit . In each episode, The Science of Skin will give you an insider’s view of the skincare industry. You will hear from research scientists, formulators, and leading physician experts on how products are developed, tested, and used to treat medical and cosmetic patients. So, if you’re interested in a behind the scenes look at what makes the skincare industry tick, subscribe to The Science of Skin today. Thanks for listening! You can also find us on YouTube: https://www.youtube.com/@scienceofskinpodcast <p

The Science of Skin is a health podcast hosted by Unknown Host, with 134 episodes on record and a Required Pod Score of 80.

Unknown Host hosts The Science of Skin, a health show with 134 episodes published.

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  Episode #134

  Can a Topical Serum Work Like Botox? Dermatologist Breaks Down P-TIOX

  Sep 29, 202620 minS5

  Can a topical serum work like a neurotoxin? Recorded live in Paris, Dr. Ted Lain sits down with Dr. Peter Bjerring to find out. Dr. Bjerring is a professor of dermatology at Aalborg University Hospital in Denmark, a laser pioneer who helped develop IPL technology, and a Knight of the Order of the Dannebrog. Together they break down SkinCeuticals P-TIOX, a serum built around two viper-venom-derived neuropeptides. One acts presynaptically, like botulinum toxin. The other blocks acetylcholine receptors on the muscle side. Both are small enough to penetrate the skin, which injectable toxins can't do. Dr. Bjerring walks through two of his clinical studies. In a split-forehead sweat study using the Minor iodine-starch test, the treated side showed little to no sweating after just three applications. That suggests the peptides really do reach their targets in the skin. In an 8-week, all-male study of 36 participants across multiple ethnicities, twice-daily use reduced forehead and glabellar lines by about 15%. Crow's feet, nasolabial folds, and even marionette lines also improved, and results kept getting better between weeks 4 and 8. The conversation also covers the supporting ingredients: 5% polyhydroxy acid for gentle exfoliation, niacinamide for barrier support, tone, and redness, and Laminaria digitata for antioxidant and collagen support. They discuss why so many self-reported sensitive-skin participants had no irritation, and how P-TIOX may pair with injectable neurotoxins to target the fine, superficial texture lines that injections miss. If you enjoyed this episode, please leave a 5-star rating and share it with a colleague. Word of mouth helps our podcast grow! Have questions or ideas for future episodes? Email us at inquiry@scienceofskinsummit.com . Disclaimer: This clip is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

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  Episode #133

  The Science of Slowing Aging: Rapamycin, Genes, and the Quest for a Longer Health Span

  Sep 22, 202637 minS5

  In this episode of the Science of Skin Podcast, Dr. Ted Lain talks with Dr. Rich Miller, professor of pathology at the University of Michigan and director of the Paul F. Glenn Center for Aging Research, about the science of slowing biological aging. Dr. Miller explains why lifespan and health span move together, not in opposition, and walks through decades of research using genetic mutants, calorie-restricted diets, and drugs like rapamycin, acarbose, canagliflozin, and 17 alpha-estradiol to extend lifespan in mice. The conversation covers how these interventions work through pathways like mTOR and glucose regulation, why some drugs affect males and females differently, and the surprising finding that many of these anti-aging effects hold up even when treatment starts in middle age rather than early in life. The two also discuss the challenge of translating mouse research to humans, Dr. Miller's work developing "aging rate indicators" that could make human drug trials for aging far more practical, and his call for more dermatology involvement in aging research — including his hope to see skin aging studied alongside the organs his lab has already examined. The episode closes with a candid take on supplement industry claims and what the current evidence actually supports for slowing aging today. ⚠️ This content is for educational and informational purposes only and reflects the personal research findings and opinions of the speakers. It is not medical advice. The discussion involves animal studies and experimental research; consult a licensed healthcare provider for questions about your own health. If you enjoyed this episode, please leave a 5-star rating and share with a colleague — word of mouth helps our podcast grow!

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  Episode #132

  Chronic Urticaria Explained: BTK Inhibitors & Remibrutinib

  Sep 15, 202620 minS5

  In this episode of the Science of Skin Podcast, Dr. Ted Lain sits down with Dr. Sarina Elmariah, MD, PhD, professor of dermatology at UC San Francisco and director of the UCSF Center for Itch and Neurosensory Disorders, for a deep dive into chronic spontaneous urticaria (CSU). Dr. Elmariah breaks down the role of Bruton's tyrosine kinase (BTK) in mast cell degranulation and explains how it sits at the center of the histamine release cascade. The conversation covers the difference between Type I (auto-allergic) and Type IIb (autoimmune) CSU pathways, available diagnostic tools like autologous serum skin testing and basophil activation testing, and why BTK appears to be a common thread across nearly all CSU mechanisms — including many inducible urticarias. The two also discuss remibrutinib (brand name Rhapsido), a BTK inhibitor newly FDA-approved for CSU, and what makes its binding mechanism distinct from earlier BTK inhibitors. They close with a look beyond histamine at the other inflammatory mediators — proteases, leukotrienes, prostaglandins, and cytokines — that help explain why so many CSU patients don't respond to antihistamines alone, and why angioedema tends to linger longer than a typical urticarial wheel. ⚠️ This content is for educational and informational purposes only and reflects the personal clinical opinions and experiences of the speakers. It is not medical advice. Consult a licensed healthcare provider for questions about diagnosis or treatment.

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  Episode #131

  K-Beauty Decoded: The Science Behind Glass Skin, Snail Mucin & Korean Sunscreens

  Sep 8, 202626 minS5

  Korean skincare is everywhere on social media — but how much of it is backed by real dermatologic science? In this episode of The Science of Skin Podcast, Dr. Patti Farris sits down with Dr. Jane Yoo, board-certified dermatologist, fellowship-trained Mohs surgeon, and "The K-Beauty Dermatologist," to separate fact from TikTok fiction. They trace K-beauty's roots from the Goryeo and Joseon dynasties through the Hallyu wave, then dig into the science: ceramide-dominant, barrier-centric formulations, low-pH cleansers, and why "glass skin" is more about consistent barrier care (and good lighting) than any single product. Dr. Yoo also breaks down the real evidence behind snail mucin, PDRN and PN, exosomes, and silica spicules — including where the hype outpaces the data — plus whether double cleansing is really necessary and why Korean sunscreen filters like bemotrizinol (Tinosorb S) may be the biggest public health advance in photoprotection in 25 years. In this episode: The real history of K-beauty, from royal court rituals to global export What actually causes "glass skin" (and what doesn't) The truth about snail mucin, PDRN/PN, exosomes, and spicules Do you really need to double cleanse? Why newly approved filters like bemotrizinol could change US sunscreens Tinted, visible-light-blocking sunscreens for skin of color Have a question or an idea for a future episode? Email inquiry@scienceofskinsummit.com. Join us at the Science of Skin Summit, September 17-20 in Austin, TX, or the new Science of Skin Longevity Conference in Scottsdale, February 2027. Learn more at scienceofskinsummit.com If you enjoyed this episode, please leave a 5-star rating and share with a colleague — word of mouth helps our podcast grow! ⚠️ This content is for educational and informational purposes only and reflects the personal clinical opinions and experiences of the speakers. It is not medical advice. Consult a licensed healthcare provider for questions about diagnosis or treatment.

  ListenShow Notes
• 

  Episode #131

  K-Beauty Decoded: The Science Behind Glass Skin, Snail Mucin & Korean Sunscreens

  Sep 8, 202626 minS5

  Korean skincare is everywhere on social media — but how much of it is backed by real dermatologic science? In this episode of The Science of Skin Podcast, Dr. Patti Farris sits down with Dr. Jane Yoo, board-certified dermatologist, fellowship-trained Mohs surgeon, and "The K-Beauty Dermatologist," to separate fact from TikTok fiction. They trace K-beauty's roots from the Goryeo and Joseon dynasties through the Hallyu wave, then dig into the science: ceramide-dominant, barrier-centric formulations, low-pH cleansers, and why "glass skin" is more about consistent barrier care (and good lighting) than any single product. Dr. Yoo also breaks down the real evidence behind snail mucin, PDRN and PN, exosomes, and silica spicules — including where the hype outpaces the data — plus whether double cleansing is really necessary and why Korean sunscreen filters like bemotrizinol (Tinosorb S) may be the biggest public health advance in photoprotection in 25 years. In this episode: The real history of K-beauty, from royal court rituals to global export What actually causes "glass skin" (and what doesn't) The truth about snail mucin, PDRN/PN, exosomes, and spicules Do you really need to double cleanse? Why newly approved filters like bemotrizinol could change US sunscreens Tinted, visible-light-blocking sunscreens for skin of color Have a question or an idea for a future episode? Email inquiry@scienceofskinsummit.com. Join us at the Science of Skin Summit, September 17-20 in Austin, TX, or the new Science of Skin Longevity Conference in Scottsdale, February 2027. Learn more at scienceofskinsummit.com ⚠️ This content is for educational and informational purposes only and reflects the personal clinical opinions and experiences of the speakers. It is not medical advice. Consult a licensed healthcare provider for questions about diagnosis or treatment.

  ListenShow Notes

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