
The Turd Nerds
#92 - SIBO Treatment Is Changing: Herbs, Probiotics & Prokinetics with Dr. Allison Siebecker
SIBO treatment continues to evolve—and Dr. Allison Siebecker is back on The Turd Nerds to break down even more of the latest research on how we treat SIBO and intestinal methanogen overgrowth (IMO). In Part 2 of our SIBO research update, we move beyond conventional antibiotics and dig into new data on herbal antimicrobials, probiotics, prokinetics, gut motility, and post-infectious IBS. We start with new human research on an herbal antimicrobial combination containing allicin, neem, and pomegranate peel, including its effects on hydrogen and methane production and SIBO symptoms. Then we tackle one of the more controversial questions in SIBO care: probiotics. Can probiotics actually improve SIBO treatment outcomes? Allison walks us through new research on Saccharomyces boulardii, Bacillus coagulans, E. coli Nissle 1917, synbiotics, and probiotics used alongside rifaximin. We also take a deeper look at two of our favorite prokinetics. New research on Iberogast suggests its benefits may extend beyond motility and symptom relief to include prebiotic, anti-inflammatory, and intestinal barrier effects. And prucalopride may be doing much more than helping patients poop—with emerging research exploring cognition, enteric nerve regeneration, visceral sensitivity, and the gut-brain connection. Finally, Allison gives us an update on research into post-infectious IBS and SIBO, including work targeting the anti-vinculin pathway that could eventually change how we approach SIBO that develops after food poisoning. IN THIS EPISODE: • New research on herbal antimicrobials for SIBO • Allicin, neem, and pomegranate peel for hydrogen and methane • Can probiotics improve SIBO treatment success? • Saccharomyces boulardii, Bacillus coagulans, and E. coli Nissle • Probiotics alongside rifaximin • Iberogast as a prokinetic, prebiotic, and gut-barrier support • Prucalopride and intestinal nerve regeneration • Prucalopride, cognition, and the gut-brain connection • Motility and visceral hypersensitivity • Anti-vinculin antibodies and post-infectious IBS • What future SIBO treatment may look like Whether you treat SIBO every day or you're trying to understand why it keeps coming back, this episode offers a look at how rapidly the SIBO treatment landscape is changing. Music provided by Blue Dot. Connect with Dr. Allison Siebecker https://www.siboinfo.com/ Connect with the Turds! Rebecca Sand ND, LAc, MSOM https://www.drrebeccasand.com/ @drrebeccasand Ilana Gurevich ND, FABNG, LAc, MSOM https://www.openwellnesspdx.com @openwellness_pdx @ilana.gurevich Ami Kapadia, MD, ABFM, ABIHM https://www.amikapadia.com/

