
The World In A Grain Of Sand
The World in a Grain of Sand: Pure Cycle
Take a deep dive into Pure Cycle with Mack Healy and Blair Willette from the team at KdT Ventures.

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The KdT Ventures team takes a deep dive into a specific S-1 filing from a company that is hoping to go public within the life science realm.
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Signup to Generate a PitchThe World In A Grain Of Sand is a business podcast hosted by KdT Ventures, with 14 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.
KdT Ventures hosts The World In A Grain Of Sand, a business show with 14 episodes published.
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The World In A Grain Of Sand
Take a deep dive into Pure Cycle with Mack Healy and Blair Willette from the team at KdT Ventures.

The World In A Grain Of Sand
<p>KdT Ventures presents The World in a Grain of Sand, where we break down an S1 from a recent biotech IPO and share insights on the science, business models, and financials. In this episode, Cain McClary and Phil Grayeski discuss BioAge, a longevity biotech with a pipeline of therapies for diseases of aging including cardiometabolic disease and neuroinflammation. Please note that this episode was recorded before the clinical readout of BioAge's apelin receptor agonist Azelaprag.<br /></p> <p>We dive into:<br /></p> BioAge's founding by first-time biotech entrepreneur Kristen Fortnoy as a Stanford spinout analyzing aging-related biomarkers<br /> Th...

The World In A Grain Of Sand
<p>KdT Ventures presents The World in a Grain of Sand, where we break down an S1 from a recent biotech IPO and share insights on the science, business models, and financials. In this episode, Cain McClary and Phil Grayeski discuss CG Oncology, the first biotech IPO of 2024. We dive into:</p> <p>The various subtypes of bladder cancer, and one of the most unique standard of care treatment paradigms in oncology, which utilizes a live attenuated virus to treat the disease</p> <p>Supply chain and manufacturing issues that have limited access to SoC therapy in bladder cancer </p> <p...

The World In A Grain Of Sand
<p>KdT Ventures presents The World in a Grain of Sand, where we break down an S1 from a recent biotech IPO and share insights on the science, business models, and financials. In this episode, Ketan Yerneni and Mack Healy discuss Verve Therapeutics, a gene editing biotech tackling one of the most common chronic diseases: cardiovascular disease. We dive into:</p> Base editing, and its advantages over traditional (potentially error-prone) CRISPR. Verve’s pipeline, including their strategy of starting with genetically well-defined diseases like familial hypercholesterolemia and then expanding to the general population of patients with atherosclerotic cardiovascular disease. Verve’s ap...

The World In A Grain Of Sand
<p>KdT Ventures presents The World in a Grain of Sand, where we break down an S1 from a recent biotech IPO and share insights on the science, business models, and financials. In this episode, Patrick Malone and Mack Healy discuss the biopharma software juggernaut, Schrödinger. We dive into:</p> Schrödinger's biophysics-based drug discovery platform, and the distinction from machine learning approaches A dissection of Schrödinger's software business, as well as co-development partnerships and internal therapeutic programs The story of Schrödinger collaboration with Nimbus on a TYK2 program, resulting in a $4B+ acquisition by Takeda and more...
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